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Damborský Jiří

Prof., Mgr., Ph.D.
Born September 29, 1969 in Brno

  • Protein and metabolic engineering
  • Member of Learned Society since 2013

Educational and professional preparation

  • 2011, Sabbatical Stay, Department of Biochemistry, University of Washington, Seattle, USA
  • 2011, Prof., Biochemistry, Faculty of Science, Masaryk University, Brno, CZ
  • 2004, EMBO YIP Networking, Bioinformatics Group, International Institute of Molecular and Cell Biology, Warsaw, PL
  • 2004, Doc., Biochemistry, Faculty of Science, Masaryk University, Brno, CZ
  • 1997, Ph.D., Microbiology, Masaryk University, Brno, CZ
  • 1997, Scholarship of the Swedish Institute, Research Group for Chemometrics, Umea University, Umea, S
  • 1997, Department of Civil and Environmental Engineering, The University of Michigan, Ann Arbor, USA
  • 1996, FEMS Fellowship, Department of Biochemistry and Department of Biophysics, University of Groningen,Groningen, NL
  • 1994, UNESCO Fellowship, International Institute for Biotechnology, University of Kent at Canterbury, Canterbury, UK
  • 1994, USIA Exchange Program Grant, Center for Environmental Biotechnology, University of Tennessee, Knoxville, USA
  • 1993, TEMPUS Student Mobility Project, Research Institute of Toxicology, University of Utrecht, Utrecht, NL
  • 1993, MSc., Microbiology, Masaryk University, Brno, CZ

Employment and academic positions

  • 2011-now, International Centre for Clinical Research, Brno, CZ
  • 2009-now, Josef Loschmidt Chair, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, CZ
  • 2007-2009, Josef Loschmidt Chair, Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, CZ
  • 2003-2007, Josef Loschmidt Chair, Faculty of Science, Masaryk University, Brno, CZ
  • 1996-2003, National Centre for Biomolecular, Faculty of Science, Masaryk University, Brno, CZ

Membership and positions in international organizations and societies

  • 2009-now, Microbial Biotechnology, Member of Editorial Board, Blackwell Publishing, USA
  • 2008-now, Current Opinion in Biotechnology, Member of Editorial Board, Elsevier, NL
  • 2005-now, Biotechnology Journal, Member of Editorial Board, Wiley-VCH, D
  • 2003-2008, Central European Journal of Chemistry, Editor, Biological Chemistry and Biochemistry, Central European Science Journals, PL
  • 2003-2008, FEMS Microbiology Reviews, Editor, Federation of European Microbiological Societies, Elsevier, NL
  • 2001-2003, Environmental Toxicology and Chemistry, Member of Editorial Board, SETAC Press, USA

Notable awards

  • 2003, European Molecular Biology Organization and Howard Hughes Medical Institute, EMBO/HHMI Scientist
  • 2003, Award of the Czech Chemical Society, Alfred Bader Prize for Bioorganic Chemistry
  • 1998, Award of the Czech Society for Biochemistry and Molecular Biology, BIOTECH
  • 1997, Award of the Czechoslovak Microbiological Society, Young Czech and Slovak Microbiologist of the Year
  • 1993, Award of the Dean of the Faculty of Science, Masaryk University

Selected publications

  • Damborský, J., Brezovský, J., 2014: Computational Methods for Designing and Engineering Biocatalysts. Current Opinion of Chemical Biology 19: 8-16.
  • Gora, A., Brezovský, J., Damborský, J., 2013: Gates of Enzymes. Chemical Reviews 113: 5871–5923.
  • Koudeláková, T., Chaloupková, R., Brezovský, J., Prokop, Z., Pavlová, M., Hessler, M., Khabiri, M., Ettrich, R., Bornscheuer, U.T., Damborský, J., 2013: Engineering Protein Resistance to Organic Co-solvent and Elevated Temperature by Access Tunnel Modification. Angewandte Chemie International Edition 52: 1959-1963.
  • Martins dos Santos, V.A.P., Damborský, J., 2010: Systems Biology at Work. Current Opinion in Biotechnology 21: 498-501.
  • Prokop, Z., Sato, Y., Brezovský, J., Mozga, T., Chaloupková, R., Koudeláková, T., Jeřábek, P., Štěpánková, V., Natsume, R., van Leeuwen, J.G.E., Janssen, D.B., Florián, J., Nagata, Y., Senda, T., Damborský, J., 2010: Enantioselectivity of Haloalkane Dehalogenases and its Modulation by Surface Loop Engineering. Angewandte Chemie 49: 6111-6115.
  • Damborský, J., Brezovský, J., 2009: Computational Tools for Designing and Engineering Biocatalysts. Current Opinion in Chemical Biology 13: 26-34.
  • Jesenská, A., Sýkora, J., Olżyńska, A., Brezovský, J., Zdráhal, Z., Damborský, J., Hof, M., 2009: Nanosecond Time-Dependent Stokes Shift at the Tunnel Mouth of Haloalkane Dehalogenases. Journal of the American Chemical Society 131: 494-501.
  • Pavelka, A., Chovancová, E., Damborský, J., 2009: HotSpot Wizard: A Web Server for Identification of Hot Spots in Protein Engineering. Nucleic Acids Research 37: W376–W383.
  • Pavlová, M., Klvaňa, M., Chaloupková, R., Banáš, P., Otyepka, M., Wade, R., Nagata, Y., Damborský, J., 2009: Redesigning Dehalogenase Access Tunnels as a Strategy for Degrading an Anthropogenic Substrate. Nature Chemical Biology 5: 727 - 733.

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News

25.07.19

Luboš Perek is celebrating his 100th year

Founding fellow of the Learned Society and its doyen, astronomer doc. RNDr. Luboš Perek, DrSc, is celebrating his 100th birthday on 26 July 2019. He is an indelible part of history as the person who helped define cosmic space, he was the first to point out the issue of cosmic waste and was also a teacher to the most important Czechoslovak astronomers. Let us express our respect and admiration of the extraordinary scientific career of a person who worked tirelessly and continues to work. The Learned Society wishes Mr Perek health, optimism and joy in the oncoming years.

23.07.19

The Academy of Sciences of the Czech Republic has appealed to the Hungarian President to support academic freedom

On Friday 19 July the Academy of Sciences of the Czech Republic and the Learned Society of the Czech Republic sent a letter to Hungarian President János Ánder, in which they state their concerns regarding the situation in respect to management and funding of scientific activities in Hungary. An act, according to which not the Academy of Sciences, but a thirteen-member political committee, will decide on research, funding of scientific activities and establishment or closure of scientific workplaces, will come into force on 1 September.

07.07.19

The loss of Learned Society Fellow prof. Josef Koutecký

We regret to inform that prof. Josef Koutecký, a fellow of the Learned Society, a renowned physician and the founder of paediatric oncology in this country, passed away on 5 July 2019 at the age of 88. He founded paediatric oncology here in 1964 and a separate paediatric oncology department was then established at the Faculty Hospital in Motol, Prague in 1978.