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Damborský Jiří

Prof., Mgr., Ph.D.
Born September 29, 1969 in Brno

  • Protein and metabolic engineering
  • Member of Learned Society since 2013

Educational and professional preparation

  • 2011, Sabbatical Stay, Department of Biochemistry, University of Washington, Seattle, USA
  • 2011, Prof., Biochemistry, Faculty of Science, Masaryk University, Brno, CZ
  • 2004, EMBO YIP Networking, Bioinformatics Group, International Institute of Molecular and Cell Biology, Warsaw, PL
  • 2004, Doc., Biochemistry, Faculty of Science, Masaryk University, Brno, CZ
  • 1997, Ph.D., Microbiology, Masaryk University, Brno, CZ
  • 1997, Scholarship of the Swedish Institute, Research Group for Chemometrics, Umea University, Umea, S
  • 1997, Department of Civil and Environmental Engineering, The University of Michigan, Ann Arbor, USA
  • 1996, FEMS Fellowship, Department of Biochemistry and Department of Biophysics, University of Groningen,Groningen, NL
  • 1994, UNESCO Fellowship, International Institute for Biotechnology, University of Kent at Canterbury, Canterbury, UK
  • 1994, USIA Exchange Program Grant, Center for Environmental Biotechnology, University of Tennessee, Knoxville, USA
  • 1993, TEMPUS Student Mobility Project, Research Institute of Toxicology, University of Utrecht, Utrecht, NL
  • 1993, MSc., Microbiology, Masaryk University, Brno, CZ

Employment and academic positions

  • 2011-now, International Centre for Clinical Research, Brno, CZ
  • 2009-now, Josef Loschmidt Chair, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, CZ
  • 2007-2009, Josef Loschmidt Chair, Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, CZ
  • 2003-2007, Josef Loschmidt Chair, Faculty of Science, Masaryk University, Brno, CZ
  • 1996-2003, National Centre for Biomolecular, Faculty of Science, Masaryk University, Brno, CZ

Membership and positions in international organizations and societies

  • 2009-now, Microbial Biotechnology, Member of Editorial Board, Blackwell Publishing, USA
  • 2008-now, Current Opinion in Biotechnology, Member of Editorial Board, Elsevier, NL
  • 2005-now, Biotechnology Journal, Member of Editorial Board, Wiley-VCH, D
  • 2003-2008, Central European Journal of Chemistry, Editor, Biological Chemistry and Biochemistry, Central European Science Journals, PL
  • 2003-2008, FEMS Microbiology Reviews, Editor, Federation of European Microbiological Societies, Elsevier, NL
  • 2001-2003, Environmental Toxicology and Chemistry, Member of Editorial Board, SETAC Press, USA

Notable awards

  • 2003, European Molecular Biology Organization and Howard Hughes Medical Institute, EMBO/HHMI Scientist
  • 2003, Award of the Czech Chemical Society, Alfred Bader Prize for Bioorganic Chemistry
  • 1998, Award of the Czech Society for Biochemistry and Molecular Biology, BIOTECH
  • 1997, Award of the Czechoslovak Microbiological Society, Young Czech and Slovak Microbiologist of the Year
  • 1993, Award of the Dean of the Faculty of Science, Masaryk University

Selected publications

  • Damborský, J., Brezovský, J., 2014: Computational Methods for Designing and Engineering Biocatalysts. Current Opinion of Chemical Biology 19: 8-16.
  • Gora, A., Brezovský, J., Damborský, J., 2013: Gates of Enzymes. Chemical Reviews 113: 5871–5923.
  • Koudeláková, T., Chaloupková, R., Brezovský, J., Prokop, Z., Pavlová, M., Hessler, M., Khabiri, M., Ettrich, R., Bornscheuer, U.T., Damborský, J., 2013: Engineering Protein Resistance to Organic Co-solvent and Elevated Temperature by Access Tunnel Modification. Angewandte Chemie International Edition 52: 1959-1963.
  • Martins dos Santos, V.A.P., Damborský, J., 2010: Systems Biology at Work. Current Opinion in Biotechnology 21: 498-501.
  • Prokop, Z., Sato, Y., Brezovský, J., Mozga, T., Chaloupková, R., Koudeláková, T., Jeřábek, P., Štěpánková, V., Natsume, R., van Leeuwen, J.G.E., Janssen, D.B., Florián, J., Nagata, Y., Senda, T., Damborský, J., 2010: Enantioselectivity of Haloalkane Dehalogenases and its Modulation by Surface Loop Engineering. Angewandte Chemie 49: 6111-6115.
  • Damborský, J., Brezovský, J., 2009: Computational Tools for Designing and Engineering Biocatalysts. Current Opinion in Chemical Biology 13: 26-34.
  • Jesenská, A., Sýkora, J., Olżyńska, A., Brezovský, J., Zdráhal, Z., Damborský, J., Hof, M., 2009: Nanosecond Time-Dependent Stokes Shift at the Tunnel Mouth of Haloalkane Dehalogenases. Journal of the American Chemical Society 131: 494-501.
  • Pavelka, A., Chovancová, E., Damborský, J., 2009: HotSpot Wizard: A Web Server for Identification of Hot Spots in Protein Engineering. Nucleic Acids Research 37: W376–W383.
  • Pavlová, M., Klvaňa, M., Chaloupková, R., Banáš, P., Otyepka, M., Wade, R., Nagata, Y., Damborský, J., 2009: Redesigning Dehalogenase Access Tunnels as a Strategy for Degrading an Anthropogenic Substrate. Nature Chemical Biology 5: 727 - 733.

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News

20.05.19

XXV. General Assembly of the Learned Society of the Czech Republic

The ceremonial part of the XXV. General Assembly of the Learned Society, at which the Medals of the Learned Society of the Czech Republic Societas Scientarium Bohemica Ad Laudem et Honorem and the awards of the Learned Society of the Czech Republic in the “Young Scientist” and “Grammar School Student” categories were presented, took place on Monday 20 May 2019 in the Great Hall of the Carolinum.

19.05.19

Bolzano lecture by prof. Kip S. Thorne

American physicist Kip S. Thorne, recipient of the Nobel Prize for 2017 for detection of gravitational waves, visited Prague at the invitation of he Learned Society. He held a series of “Bolzano lectures” and a lecture titled “Creating Gravitational-Wave Astronomy” for the Learned Society on 15 May 2019 in the Blue Auditorium of the Carolinum. The lecture was held with the support of the Karel Janeček Foundation and was received very enthusiastically.

07.05.19

XXV. General Assembly

The Czech Learned Society is holding its XXV. General Assembly on 20 and 21 May 2019. The Learned Society’s awards in the “Young Scientist” and “Grammar School Student” categories, Teaching Awards for pedagogic workers who promote interest in science and research at grammar schools and the Learned Society’s medals for meritorious contributions to the advance of science will be presented during a ceremony on 20 May at the Karolinum. Lectures by renowned scientists will also be presented. The second day will be reserved for the working part of the meeting, in the building of the Academy of Sciences of the Czech Republic.