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Damborský Jiří

Prof., Mgr., Ph.D.
Born September 29, 1969 in Brno

  • Protein and metabolic engineering
  • Member of Learned Society since 2013

Educational and professional preparation

  • 2011, Sabbatical Stay, Department of Biochemistry, University of Washington, Seattle, USA
  • 2011, Prof., Biochemistry, Faculty of Science, Masaryk University, Brno, CZ
  • 2004, EMBO YIP Networking, Bioinformatics Group, International Institute of Molecular and Cell Biology, Warsaw, PL
  • 2004, Doc., Biochemistry, Faculty of Science, Masaryk University, Brno, CZ
  • 1997, Ph.D., Microbiology, Masaryk University, Brno, CZ
  • 1997, Scholarship of the Swedish Institute, Research Group for Chemometrics, Umea University, Umea, S
  • 1997, Department of Civil and Environmental Engineering, The University of Michigan, Ann Arbor, USA
  • 1996, FEMS Fellowship, Department of Biochemistry and Department of Biophysics, University of Groningen,Groningen, NL
  • 1994, UNESCO Fellowship, International Institute for Biotechnology, University of Kent at Canterbury, Canterbury, UK
  • 1994, USIA Exchange Program Grant, Center for Environmental Biotechnology, University of Tennessee, Knoxville, USA
  • 1993, TEMPUS Student Mobility Project, Research Institute of Toxicology, University of Utrecht, Utrecht, NL
  • 1993, MSc., Microbiology, Masaryk University, Brno, CZ

Employment and academic positions

  • 2011-now, International Centre for Clinical Research, Brno, CZ
  • 2009-now, Josef Loschmidt Chair, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, CZ
  • 2007-2009, Josef Loschmidt Chair, Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, CZ
  • 2003-2007, Josef Loschmidt Chair, Faculty of Science, Masaryk University, Brno, CZ
  • 1996-2003, National Centre for Biomolecular, Faculty of Science, Masaryk University, Brno, CZ

Membership and positions in international organizations and societies

  • 2009-now, Microbial Biotechnology, Member of Editorial Board, Blackwell Publishing, USA
  • 2008-now, Current Opinion in Biotechnology, Member of Editorial Board, Elsevier, NL
  • 2005-now, Biotechnology Journal, Member of Editorial Board, Wiley-VCH, D
  • 2003-2008, Central European Journal of Chemistry, Editor, Biological Chemistry and Biochemistry, Central European Science Journals, PL
  • 2003-2008, FEMS Microbiology Reviews, Editor, Federation of European Microbiological Societies, Elsevier, NL
  • 2001-2003, Environmental Toxicology and Chemistry, Member of Editorial Board, SETAC Press, USA

Notable awards

  • 2003, European Molecular Biology Organization and Howard Hughes Medical Institute, EMBO/HHMI Scientist
  • 2003, Award of the Czech Chemical Society, Alfred Bader Prize for Bioorganic Chemistry
  • 1998, Award of the Czech Society for Biochemistry and Molecular Biology, BIOTECH
  • 1997, Award of the Czechoslovak Microbiological Society, Young Czech and Slovak Microbiologist of the Year
  • 1993, Award of the Dean of the Faculty of Science, Masaryk University

Selected publications

  • Damborský, J., Brezovský, J., 2014: Computational Methods for Designing and Engineering Biocatalysts. Current Opinion of Chemical Biology 19: 8-16.
  • Gora, A., Brezovský, J., Damborský, J., 2013: Gates of Enzymes. Chemical Reviews 113: 5871–5923.
  • Koudeláková, T., Chaloupková, R., Brezovský, J., Prokop, Z., Pavlová, M., Hessler, M., Khabiri, M., Ettrich, R., Bornscheuer, U.T., Damborský, J., 2013: Engineering Protein Resistance to Organic Co-solvent and Elevated Temperature by Access Tunnel Modification. Angewandte Chemie International Edition 52: 1959-1963.
  • Martins dos Santos, V.A.P., Damborský, J., 2010: Systems Biology at Work. Current Opinion in Biotechnology 21: 498-501.
  • Prokop, Z., Sato, Y., Brezovský, J., Mozga, T., Chaloupková, R., Koudeláková, T., Jeřábek, P., Štěpánková, V., Natsume, R., van Leeuwen, J.G.E., Janssen, D.B., Florián, J., Nagata, Y., Senda, T., Damborský, J., 2010: Enantioselectivity of Haloalkane Dehalogenases and its Modulation by Surface Loop Engineering. Angewandte Chemie 49: 6111-6115.
  • Damborský, J., Brezovský, J., 2009: Computational Tools for Designing and Engineering Biocatalysts. Current Opinion in Chemical Biology 13: 26-34.
  • Jesenská, A., Sýkora, J., Olżyńska, A., Brezovský, J., Zdráhal, Z., Damborský, J., Hof, M., 2009: Nanosecond Time-Dependent Stokes Shift at the Tunnel Mouth of Haloalkane Dehalogenases. Journal of the American Chemical Society 131: 494-501.
  • Pavelka, A., Chovancová, E., Damborský, J., 2009: HotSpot Wizard: A Web Server for Identification of Hot Spots in Protein Engineering. Nucleic Acids Research 37: W376–W383.
  • Pavlová, M., Klvaňa, M., Chaloupková, R., Banáš, P., Otyepka, M., Wade, R., Nagata, Y., Damborský, J., 2009: Redesigning Dehalogenase Access Tunnels as a Strategy for Degrading an Anthropogenic Substrate. Nature Chemical Biology 5: 727 - 733.

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Reaction to the case of Tomáš Hudlický: Members of the Learned Society of the Czech Republic support the freedom of expression

„We believe that free exchange of ideas is a key condition for the pursuit of truth and that the honest opinions should be scrutinized, challenged or rebutted but not censored or suppressed,“ say 45 members of the Learned Society in a statement regarding the retracted opinion paper by Prof. Tomáš Hudlický.


The letter by Jan Konvalinka to the President and Vice-Chancellor of the Brock University regarding the retracted article of Prof. Tomáš Hudlický

Opinions could and should be challenged, questioned or refuted but never silenced. In order to be able to think, we have to have the right to inquire, question and even offend or be mistaken,” writes Assoc. Prof. Jan Konvalinka, a biochemist at the IOCB Prague and the Vice-Rector of the Charles University, to Gervan Fearon.


Prof Miroslav Bárta receives the Česká hlava National Government Award

Learned Society member, Prof. Mgr. Miroslav Bárta, Dr. (Charles University Faculty of Arts) received the Česká hlava (Czech Head) National Government Award on 25 November 2019. A renowned Czech Egyptologist and archaeologist, Professor Bárta researches the history of ancient civilisations, the human relationship to the natural environment, and also for many years the evolution of complex societies. He leads the Czech Institute of Egyptology for archaeological and environmental research in Egypt and Sudan. His principal research interest is the period of the pyramid builders of the Old Kingdom.