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Forejt Jiří

Prof., MUDr., DrSc., DSc. 
Born on December 28, 1944

  • Molecular genetics and genomics of laboratory mice
  • Member of Learned Society since 1999

Educational and professional preparation

  • 1962-68, MUDr. Faculty of Medicine, Charles University, Hradec Králové;
  • 1975, CSc. in genetics, Institute of Molecular Genetics, CSAS, Prague;
  • 1991, DrSc. in genetics, Charles University, Prague;
  • 2002, Associate Professor, molecular biology and genetics, Faculty of Science CU
  • 2006, Full professor, molecular biology and genetics, Faculty of Science CU

Employment and academic positions

  • 1968-present, Institute of Molecular Genetics, AS CR (originally Institute of Experimental Biology and Genetics, CSAS);
  • 1980-present, Head, Department of Molecular Genetics (originally the Department of Developmental Genetics);
  • 1992-1993, 1995-1996, Visiting Professor, Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA

Membership in domestic scientific bodies

  • 2003-present, Chairman, Commission for Granting Title of DSc. in Genetics and Genomics
  • 2001-2005, Vice-Chairman, Council for Sciences AS CR

Membership and positions in selected international organizations and societies

  • 1984-1991, Elected member, Internat. Committee for Standardized Mouse Genetic Nomenclature
  • 1991-present, International Mammalian Genome Society
  • 1998-2001, Chairman, Chromosome 17 Committee
  • 1996-present, Howard Hughes Medical Institute–International Scholar
  • 1999-present, European Molecular Biology Organization-Elected member
  • 1998-present, Slovak Commissions for Defence of Doctoral Theses - 15-02-9, 15-01-9 and 15-16-9
  • 2003-2006, Member, EMBO YIP Selection Committee
  • 2003-2007, Elected member, Secretariat, International Mammalian Genome Society
  • 2008 –present, member, Scientific Advisory Board, Consortium of an Integrated Genome Research Network, Max-Planck-Institute for Molecular Genetics, Berlin
  • Member, editorial boards (in the past and present): Cytogenetics and Cell Genetics, Mouse Genome, Experimental and Clinical Immunogenetics, Roux Archives of Developmental Biology, Mammalian Genome, Folia Biologica.
    Ad hoc reviewer for: Proceedings of National Academy of Sciences USA, Genomics, Genes and Development, Genetical Research, Genome research, Genetics, J. Andrology, Gene.
  • Main organizer, international symposia: 1983, Molecular Biology of Embryonic and Teratocarcinoma Stem Cells; 1990, VIIth International Workshop of Mouse Molecular Genetics; 1996, Howard Hughes Medical Institute Conference of International Fellows- (Chairman, local organization committee), 22nd International Mouse Genome Conference, Prague, 2008.

Notable awards

  • 1984, Prize, CSAS
  • 1999, 2009, Prize, AS CR
  • 2004, Gregor Mendel Medal, AS CR
  • 2007-2013, Praemium Academiae, AS CR
  • 2009, Prize, Ministry of Education, Youth and Sports

Selected publications

  • Forejt, J.: Spermatogenic failure of translocation heterozygotes affected by H-2 linked gene in mouse. Nature (London) 260,143-145, 1976
  • Forejt, J.: X-inactivation and its role in male sterility. In: Chromosomes Today, Vol. 8 (A.Gropp, M. D.Bennett and U. Wolf, Eds.) George Allen and Unwin, Hemel Hempstead (England) 1984, p.117-127
  • Forejt, J., Gregorova, S., Dohnal, K., Nosek, J.: Gene expression of differentiated parent in teratocarcinoma cell hybrids. Repression or reprogramming? Cell Differ. 15, 129-134, 1984.
  • Kralova, J., Jansa, P., Forejt, J.: A novel downstream regulatory element of the mouse H-2K b class I major histocompatibility gene. EMBO J. 11, 4591-4600,1992
  • Forejt, J., Gregorova, S.: Genetic analysis of genomic imprinting: An Imprintor-1 gene controls inactivation of the paternal copy of the mouse Tme locus. Cell 70, 443-450, 1992
  • Forejt, J.: Hybrid sterility in the mouse. Trend. Genet. 12, 412-417, 1996
  • Forejt, J.: Nondisjuction. In: Encyclopedia of Genetics. S. Brenner and J. Miller, Eds. Academic Press, London New York, 2001, pp. 1345-1347
  • Divina, P., Forejt, J.: The mouse SAGE site: database of public mouse SAGE libraries. Nucl. Acid. Res. 32, D482-D483, 2004
  • Homolka, D., Ivanek, R., Capkova, J., Jansa, P., Forejt, J.: Chromosomal rearrangement interferes with meiotic X-chromosome inactivation. Genome Research 17, 1431-1437, 2007
  • Gregorová, S., Divina, P., Storchova, R., Trachtulec, Z., Fotopulosova, V., Svenson, K.L., Donahue, L.R., Paigen, B., Forejt, J.: Mouse consomic strains: Exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Research 18, 509-505, 2008.
  • Mihola, O., Trachtulec, Z., Vlcek, C., Schimenti, J.C., Forejt, J: A mouse speciation gene encodes a meiotic Histone H3 methyltransferase. Science 323, 373—375, 2009

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XXV. General Assembly of the Learned Society of the Czech Republic

The ceremonial part of the XXV. General Assembly of the Learned Society, at which the Medals of the Learned Society of the Czech Republic Societas Scientarium Bohemica Ad Laudem et Honorem and the awards of the Learned Society of the Czech Republic in the “Young Scientist” and “Grammar School Student” categories were presented, took place on Monday 20 May 2019 in the Great Hall of the Carolinum.


Bolzano lecture by prof. Kip S. Thorne

American physicist Kip S. Thorne, recipient of the Nobel Prize for 2017 for detection of gravitational waves, visited Prague at the invitation of he Learned Society. He held a series of “Bolzano lectures” and a lecture titled “Creating Gravitational-Wave Astronomy” for the Learned Society on 15 May 2019 in the Blue Auditorium of the Carolinum. The lecture was held with the support of the Karel Janeček Foundation and was received very enthusiastically.


XXV. General Assembly

The Czech Learned Society is holding its XXV. General Assembly on 20 and 21 May 2019. The Learned Society’s awards in the “Young Scientist” and “Grammar School Student” categories, Teaching Awards for pedagogic workers who promote interest in science and research at grammar schools and the Learned Society’s medals for meritorious contributions to the advance of science will be presented during a ceremony on 20 May at the Karolinum. Lectures by renowned scientists will also be presented. The second day will be reserved for the working part of the meeting, in the building of the Academy of Sciences of the Czech Republic.