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Pačes Václav

Prof., RNDr., DrSc., Dr.h.c.
Born February 2, 1942

  • Genomics
  • Member of Learned Society since 1994 (Founding member)
  • 2000, Vice-Chairman
  • 1998-2002, member, Council of LS

Educational and professional preparation:

  • 1959, IV. Qualification class: press operator, welder, ČKD Vagónka Tatra Smíchov, Praha;
  • 1965, graduate, biochemistry, Faculty of Natural Sciences, Charles University, Prague;
  • 1970, RNDr.; 1968, CSc.(PhD), Institute of Organic Chemistry and Biochemistry, CSAS (IOCB), Prague;
  • 1988, DrSc., Institute of Molecular Genetics, CSAS;
  • 1990, Associate Professor of biochemistry, Institute of Chemical Technology (ICT), Prague;
  • 1994, Full Professor of biochemistry, ICT.

Employment and academic positions:

  • 1965-1968, PhD student, IOCB, CSAS;
  • 1968-1969, Research associate, Department of Biophysics and Theoretical Biology, University of Chicago, USA;
  • 1969-1970, Post-doctoral student, Department of Biochemistry, McMaster University, Hamilton, Ontario, Canada;
  • 1970-1977, scientist and later senior scientist, IOCB, CSAS;
  • 1977-present, Head, Department of Genomics and Bioinformatics, Institute of Molecular Genetics, CSAS and AS CR;
  • 1990-1991, Visiting scientist, Human Genetics Department, Yale University, New Haven, USA.
  • Shorter stays by invitation: 1980, Department of Biochemistry, University of Bristol, England; 1986, Institute of Molecular Biology, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain; 1988, Department of Genetics, University of Seville, Spain, (organized course on DNA sequencing); 1989, Institute of Applied Biochemistry, Mitake, Japan; invited lecture at the Federation of European Biochemical Societies (FEBS) Congress, Rome 1989;
  • 1994-1997, Vice-President, AS CR;
  • 1999-present, Director, Institute of Molecular Genetics, AS CR;
  • 2005-present, president, AS CR;

Membership in selected domestic scientific bodies:

  • Czech Society for Biochemistry and Molecular Biology (Chairman since 1990)

Membership and positions in international organizations and societies:

  • Member, steering committee, NATO Program Science (for Peace)
  • 1997, elected member, European Molecular Biology Organisation (EMBO)
  • 2000, Vice-Chairman, European Molecular Biology Conference (EMBC)
  • 1997, elected member, European Academy of Sciences and Arts
  • 2002, elected member, European Academy of Sciences
  • 2002, elected member, Publications Committee, FEBS; editor, journal, Gene
  • 2002, member, editorial board, European Journal of Biochemistry
  • 2003, editor, Research in Microbiology

Notable awards:

  • 1980, Prize, Czech Literary Fund (for the best publication)
  • 1987, Award, CSAS
  • 1989, State award (for science)
  • 1992, CSAS award (for promotion of science)
  • 1988, Annual lecture in honour of J. L. Fischer, Palacký University

Selected publications:

  • Pačes V., Doskočil J., Šorm F.: Incorporation of 5-azacytidine into nucleic acids of Escherichia coli. Biochim. Biophys. Acta 161, 352-360 (1968)
  • Pačes V., Doskočil J., Šorm F.: The effect of 5-azacytidine on the synthesis of ribosomes in Escherichia coli. FEBS Letters 1, 55-58 (1968)
  • Pačes V., Werstiuk E., Hall R. H.: Conversion of N6(isopentenyl)ade-nosine to adenosine by enzyme activity in tobacco tissue. Plant Physiol. 48, 775-778 (1971)
  • Pačes V., Vlček C., Urbánek P.: Nucleotide sequence of the late region of Bacillus subtilis phage PZA, a close relative of j29. Gene 44, 107-114 (1986)
  • Hostomský Z., Smrt J., Arnold L., Točík Z., Pačes V.: Solid-phase assembly of cow colostrum trypsin inhibitor gene. Nucleic Acids Res. 15, 4849-4856 (1987)
  • Kozmík Z., Arnold L., Pačes V.: Multiple sets of adjacent mE1 and oct-1 binding sites upstream of the pseudorabies virus immediate-early gene promoter. Virology 182, 239-249 (1991)
  • Pačes V., Rosenberg L.E., Fenton V., Kalousek F.: The b-subunit of the mitochondrial processing peptidase from rat liver: gene cloning and sequencing and comparison to a new family of metallopeptidases. Proc. Natl. Acad. Sci. USA 90 (1993) 5355-5358
  • Dujon B. et al. (98 authors, Beneš V., Pačes V., Vlček Č. included): The complete nucleotide sequence of yeast chromosome XV. Nature 387, 98-102 (l997)
  • Pačes V., Pivec L., Teich A. (Eds.): Science Evaluation and Its Management. IOS Press, Amsterdam 1999
  • Pečenková T., Pačes V.: Molecular phylogeny of j29-like phages and their relatedness to other protein-primed replicating phages and other phages hosted by gram-positive bacteria. J. Mol. Evol. 48, 197-208 (1999)
  • Pačes J., Pavlíček A., Pačes V.: HERVd: database of human endogenous retroviruses, Nucleic Acids Res. 30, 205-206 (2002)
  • Ruivenkamp A.L., ….Vlček Č….Pačes V….Démant P. (20 authors in total): Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers. Nature Genetics 31, 295-300 (2002)
  • Pačes J., Pavlíček A., Zika R., Kapitonov V.V., Jurka J., Pačes V.: HERVd: the Human Endogenous Retroviruses Database. Update Nucleic Acids Res. 32, 50 (2004)

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XXV. General Assembly of the Learned Society of the Czech Republic

The ceremonial part of the XXV. General Assembly of the Learned Society, at which the Medals of the Learned Society of the Czech Republic Societas Scientarium Bohemica Ad Laudem et Honorem and the awards of the Learned Society of the Czech Republic in the “Young Scientist” and “Grammar School Student” categories were presented, took place on Monday 20 May 2019 in the Great Hall of the Carolinum.


Bolzano lecture by prof. Kip S. Thorne

American physicist Kip S. Thorne, recipient of the Nobel Prize for 2017 for detection of gravitational waves, visited Prague at the invitation of he Learned Society. He held a series of “Bolzano lectures” and a lecture titled “Creating Gravitational-Wave Astronomy” for the Learned Society on 15 May 2019 in the Blue Auditorium of the Carolinum. The lecture was held with the support of the Karel Janeček Foundation and was received very enthusiastically.


XXV. General Assembly

The Czech Learned Society is holding its XXV. General Assembly on 20 and 21 May 2019. The Learned Society’s awards in the “Young Scientist” and “Grammar School Student” categories, Teaching Awards for pedagogic workers who promote interest in science and research at grammar schools and the Learned Society’s medals for meritorious contributions to the advance of science will be presented during a ceremony on 20 May at the Karolinum. Lectures by renowned scientists will also be presented. The second day will be reserved for the working part of the meeting, in the building of the Academy of Sciences of the Czech Republic.