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Tlaskalová – Hogenová Helena

Prof., M.D., DSc.
Born December 29, 1938 in Prague

  • Immunology, mucosal and developmental immunology
  • Member of Learned Society since 2000

Educational and professional preparation:

  • 1957-1962, Faculty of General Medicine, Charles University (CU), Prague;
  • 1968, PhD, Institute of Microbiology (IMB), CSAS, Prague;
  • 1994, DSc. Academy of Sciences of Czech Republic (AS CR);
  • 1995, Associate Professor, First Faculty of Medicine (FFM), CU;
  • 2001, Full Professor, FFM, CU

Employment and academic positions:

  • 1962-1964, Physician, Hospital, Ústí nad Labem;
  • 1964-1968, post-graduate student, IMB, CSAS;
  • 1968-present, IMB AS CR, from 1991-2003, Head, Division of Immunology and Gnotobiology)

Membership in selected Czech scientific organizations:

  • Member, Committee of Czech Immunological Society (Chair, 1996-2001)
  • Member, Committee of Czech Society of Allergology and Clinical Immunology (J. E. Purkyně Medical Society)
  • Member, Central Commission for Protection of Animals in Czech Republic
  • Scientific Councils: FFM, CU, Motol Faculty Hospital, IMB and Institute of Physiology, AS CR
  • 2003-present, Chair, Commission for Defence of Doctoral Theses in immunology at AS CR
  • Member, Council for the Doctoral Study Programme in Immunology

Membership and positions in international organizations and societies:

  • 1995-2001, Member, Council of International Union of Immunological Societies
  • 1999-2003, Member, External Advisory Group (EAG), European Commission, Life Sciences “Control of Infectious Diseases”
  • International Society for Mucosal Immunology
  • International Society of Developmental and Comparative Immunology
  • Member, organizational committees of a number of international congresses and symposia
  • Member, Editorial Boards of, International Medical Magazine, Central-European Journal of Immunology, Alergie

Notable awards:

  • 1981, 1982, Awards of CSAS
  • 1987, J.E. Purkyně Medal, awarded by CSAS
  • 1996, Award, Gastroenterological Society
  • 1997, Award, Faculty of Medicine (for work in the area of mucosal immunity)
  • 1999, Medal, Nihon University, Tokyo, Japan

Selected publications:

  • Jelínková L., Tučková L., Cinová J., Flegelová Z., Tlaskalová-Hogenová H.: Gliadin stimulates human monocytes to production of IL-8 and TNF-á through a mechanism involving NF-ęB. FEBS Letters 571, 81-85, 2004
  • D. Sánchez, L. Tučková, Th. Mothes, W. Kreisel, Z. Beneš, H. Tlaskalová-Hogenová: Epitopes of calreticulin recognised by IgA autoantibodies from patients with hepatic and coeliac disease. J. Of Autoimmunity 21, 383-392, 2003
  • H. Tlaskalová-Hogenová, L. Tučková, R. Lodinová-Žádníková, R. Štěpánková, B. Cukrowska, D. P. Funda, I. Stříž, H. Kozáková, I. Trebichavský, D. Sokol., Z. Řeháková, J. Šinkora, P. Fundová, D. Horáková, L. Jelínková, D. Sánchez: Mucosal Immunity: Its role in defense and allergy. Int. Arch. Allergy Immunol. 128, 77-89 (2002)
  • D. P. Funda, L. Tučková, M. A. Farré, T. Iwase, I. Moro, H. Tlaskalová-Hogenová: CD14 is expressed and released as soluble CD14 by human intestinal epithelial cells in vitro: Lipopolysaccharide activation of epithelial cells revisited. Infection and Immunity 69, 3772-3781 (2001)
  • B. Singh, S. Read, Ch. Asseman, V. Malmstrom, Ch. Mottet, L. A. Stephans, R. Štěpánková, H. Tlaskalová, F. Powrie: Control of intestinal inflammation by regulatory T cells. Immunol. Rev. 182, 190-200 (2001)
  • D. P. Funda, A. Kaas, T. Bock, H. Tlaskalová-Hogenová, K. Buschard: Gluten-free diet prevents diabetes in NOD mice. Diabetes/Metabolism Research and Reviews 15, 323-327 (1999)
  • S. Krupičková, L. Tučková, Z. Flegelová, M. Michalak, J. R. F. Walters, A. Whelan, J. Harries, J. Vencovský, H. Tlaskalová-Hogenová: Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac diasease. Gut 44, 168-173 (1999)
  • H. Tlaskalová-Hogenová, R. Štěpánková, L. Tučková, B. Cukrowska, T. Hudcovic, F. Bendjelloul, P. Malý, M. Jirkovská, V. Mandys, O. Kofroňová, E. F. Verdú, P. Berčík, M. Farre, L. Prokešová, D. P. Funda, H. Kozáková, P. Michetti, J. Cebra: Effector mechanisms in intestinal immunity and inflammation. In: Innovative concepts in inflammatory bowel diseases (Emmrich et al., Eds.), Kluwer Academic Publishers, Dordrecht/Boston/London 1999, pp. 74-83
  • J. Mestecky, M. Russell, S. Jackson, S. Michalak, H. Tlaskalová-Hogenová, J. Šterzl (Eds.): Advances in Mucosal Immunology. Plenum Press, New York 1995
  • H. Tlaskalová-Hogenová, J. Šterzl, R. Štěpánková, V. Dlabač, V. Větvička, P. Rossmann, L. Mandel, J. Rejnek: Development of immunological capacity under germ-free and conventional conditions. Ann. N. Y. Acad. Sci. 409, 96-113 (1983)
  • M. Holub, P. Rossmann, H. Tlaskalová, H. Vidmarová: Thymus rudiment of the athymic nude mouse. Nature 256, 491-493 (1975)

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XXV. General Assembly of the Learned Society of the Czech Republic

The ceremonial part of the XXV. General Assembly of the Learned Society, at which the Medals of the Learned Society of the Czech Republic Societas Scientarium Bohemica Ad Laudem et Honorem and the awards of the Learned Society of the Czech Republic in the “Young Scientist” and “Grammar School Student” categories were presented, took place on Monday 20 May 2019 in the Great Hall of the Carolinum.


Bolzano lecture by prof. Kip S. Thorne

American physicist Kip S. Thorne, recipient of the Nobel Prize for 2017 for detection of gravitational waves, visited Prague at the invitation of he Learned Society. He held a series of “Bolzano lectures” and a lecture titled “Creating Gravitational-Wave Astronomy” for the Learned Society on 15 May 2019 in the Blue Auditorium of the Carolinum. The lecture was held with the support of the Karel Janeček Foundation and was received very enthusiastically.


XXV. General Assembly

The Czech Learned Society is holding its XXV. General Assembly on 20 and 21 May 2019. The Learned Society’s awards in the “Young Scientist” and “Grammar School Student” categories, Teaching Awards for pedagogic workers who promote interest in science and research at grammar schools and the Learned Society’s medals for meritorious contributions to the advance of science will be presented during a ceremony on 20 May at the Karolinum. Lectures by renowned scientists will also be presented. The second day will be reserved for the working part of the meeting, in the building of the Academy of Sciences of the Czech Republic.