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Tlaskalová – Hogenová Helena

Prof., M.D., DSc.
Born December 29, 1938 in Prague

  • Immunology, mucosal and developmental immunology
  • Member of Learned Society since 2000

Educational and professional preparation:

  • 1957-1962, Faculty of General Medicine, Charles University (CU), Prague;
  • 1968, PhD, Institute of Microbiology (IMB), CSAS, Prague;
  • 1994, DSc. Academy of Sciences of Czech Republic (AS CR);
  • 1995, Associate Professor, First Faculty of Medicine (FFM), CU;
  • 2001, Full Professor, FFM, CU

Employment and academic positions:

  • 1962-1964, Physician, Hospital, Ústí nad Labem;
  • 1964-1968, post-graduate student, IMB, CSAS;
  • 1968-present, IMB AS CR, from 1991-2003, Head, Division of Immunology and Gnotobiology)

Membership in selected Czech scientific organizations:

  • Member, Committee of Czech Immunological Society (Chair, 1996-2001)
  • Member, Committee of Czech Society of Allergology and Clinical Immunology (J. E. Purkyně Medical Society)
  • Member, Central Commission for Protection of Animals in Czech Republic
  • Scientific Councils: FFM, CU, Motol Faculty Hospital, IMB and Institute of Physiology, AS CR
  • 2003-present, Chair, Commission for Defence of Doctoral Theses in immunology at AS CR
  • Member, Council for the Doctoral Study Programme in Immunology

Membership and positions in international organizations and societies:

  • 1995-2001, Member, Council of International Union of Immunological Societies
  • 1999-2003, Member, External Advisory Group (EAG), European Commission, Life Sciences “Control of Infectious Diseases”
  • International Society for Mucosal Immunology
  • International Society of Developmental and Comparative Immunology
  • Member, organizational committees of a number of international congresses and symposia
  • Member, Editorial Boards of, International Medical Magazine, Central-European Journal of Immunology, Alergie

Notable awards:

  • 1981, 1982, Awards of CSAS
  • 1987, J.E. Purkyně Medal, awarded by CSAS
  • 1996, Award, Gastroenterological Society
  • 1997, Award, Faculty of Medicine (for work in the area of mucosal immunity)
  • 1999, Medal, Nihon University, Tokyo, Japan

Selected publications:

  • Jelínková L., Tučková L., Cinová J., Flegelová Z., Tlaskalová-Hogenová H.: Gliadin stimulates human monocytes to production of IL-8 and TNF-á through a mechanism involving NF-ęB. FEBS Letters 571, 81-85, 2004
  • D. Sánchez, L. Tučková, Th. Mothes, W. Kreisel, Z. Beneš, H. Tlaskalová-Hogenová: Epitopes of calreticulin recognised by IgA autoantibodies from patients with hepatic and coeliac disease. J. Of Autoimmunity 21, 383-392, 2003
  • H. Tlaskalová-Hogenová, L. Tučková, R. Lodinová-Žádníková, R. Štěpánková, B. Cukrowska, D. P. Funda, I. Stříž, H. Kozáková, I. Trebichavský, D. Sokol., Z. Řeháková, J. Šinkora, P. Fundová, D. Horáková, L. Jelínková, D. Sánchez: Mucosal Immunity: Its role in defense and allergy. Int. Arch. Allergy Immunol. 128, 77-89 (2002)
  • D. P. Funda, L. Tučková, M. A. Farré, T. Iwase, I. Moro, H. Tlaskalová-Hogenová: CD14 is expressed and released as soluble CD14 by human intestinal epithelial cells in vitro: Lipopolysaccharide activation of epithelial cells revisited. Infection and Immunity 69, 3772-3781 (2001)
  • B. Singh, S. Read, Ch. Asseman, V. Malmstrom, Ch. Mottet, L. A. Stephans, R. Štěpánková, H. Tlaskalová, F. Powrie: Control of intestinal inflammation by regulatory T cells. Immunol. Rev. 182, 190-200 (2001)
  • D. P. Funda, A. Kaas, T. Bock, H. Tlaskalová-Hogenová, K. Buschard: Gluten-free diet prevents diabetes in NOD mice. Diabetes/Metabolism Research and Reviews 15, 323-327 (1999)
  • S. Krupičková, L. Tučková, Z. Flegelová, M. Michalak, J. R. F. Walters, A. Whelan, J. Harries, J. Vencovský, H. Tlaskalová-Hogenová: Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac diasease. Gut 44, 168-173 (1999)
  • H. Tlaskalová-Hogenová, R. Štěpánková, L. Tučková, B. Cukrowska, T. Hudcovic, F. Bendjelloul, P. Malý, M. Jirkovská, V. Mandys, O. Kofroňová, E. F. Verdú, P. Berčík, M. Farre, L. Prokešová, D. P. Funda, H. Kozáková, P. Michetti, J. Cebra: Effector mechanisms in intestinal immunity and inflammation. In: Innovative concepts in inflammatory bowel diseases (Emmrich et al., Eds.), Kluwer Academic Publishers, Dordrecht/Boston/London 1999, pp. 74-83
  • J. Mestecky, M. Russell, S. Jackson, S. Michalak, H. Tlaskalová-Hogenová, J. Šterzl (Eds.): Advances in Mucosal Immunology. Plenum Press, New York 1995
  • H. Tlaskalová-Hogenová, J. Šterzl, R. Štěpánková, V. Dlabač, V. Větvička, P. Rossmann, L. Mandel, J. Rejnek: Development of immunological capacity under germ-free and conventional conditions. Ann. N. Y. Acad. Sci. 409, 96-113 (1983)
  • M. Holub, P. Rossmann, H. Tlaskalová, H. Vidmarová: Thymus rudiment of the athymic nude mouse. Nature 256, 491-493 (1975)

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Reaction to the case of Tomáš Hudlický: Members of the Learned Society of the Czech Republic support the freedom of expression

„We believe that free exchange of ideas is a key condition for the pursuit of truth and that the honest opinions should be scrutinized, challenged or rebutted but not censored or suppressed,“ say 45 members of the Learned Society in a statement regarding the retracted opinion paper by Prof. Tomáš Hudlický.


The letter by Jan Konvalinka to the President and Vice-Chancellor of the Brock University regarding the retracted article of Prof. Tomáš Hudlický

Opinions could and should be challenged, questioned or refuted but never silenced. In order to be able to think, we have to have the right to inquire, question and even offend or be mistaken,” writes Assoc. Prof. Jan Konvalinka, a biochemist at the IOCB Prague and the Vice-Rector of the Charles University, to Gervan Fearon.


Prof Miroslav Bárta receives the Česká hlava National Government Award

Learned Society member, Prof. Mgr. Miroslav Bárta, Dr. (Charles University Faculty of Arts) received the Česká hlava (Czech Head) National Government Award on 25 November 2019. A renowned Czech Egyptologist and archaeologist, Professor Bárta researches the history of ancient civilisations, the human relationship to the natural environment, and also for many years the evolution of complex societies. He leads the Czech Institute of Egyptology for archaeological and environmental research in Egypt and Sudan. His principal research interest is the period of the pyramid builders of the Old Kingdom.