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Tlaskalová – Hogenová Helena

Prof., M.D., DSc.
Born December 29, 1938 in Prague

  • Immunology, mucosal and developmental immunology
  • Member of Learned Society since 2000

Educational and professional preparation:

  • 1957-1962, Faculty of General Medicine, Charles University (CU), Prague;
  • 1968, PhD, Institute of Microbiology (IMB), CSAS, Prague;
  • 1994, DSc. Academy of Sciences of Czech Republic (AS CR);
  • 1995, Associate Professor, First Faculty of Medicine (FFM), CU;
  • 2001, Full Professor, FFM, CU

Employment and academic positions:

  • 1962-1964, Physician, Hospital, Ústí nad Labem;
  • 1964-1968, post-graduate student, IMB, CSAS;
  • 1968-present, IMB AS CR, from 1991-2003, Head, Division of Immunology and Gnotobiology)

Membership in selected Czech scientific organizations:

  • Member, Committee of Czech Immunological Society (Chair, 1996-2001)
  • Member, Committee of Czech Society of Allergology and Clinical Immunology (J. E. Purkyně Medical Society)
  • Member, Central Commission for Protection of Animals in Czech Republic
  • Scientific Councils: FFM, CU, Motol Faculty Hospital, IMB and Institute of Physiology, AS CR
  • 2003-present, Chair, Commission for Defence of Doctoral Theses in immunology at AS CR
  • Member, Council for the Doctoral Study Programme in Immunology

Membership and positions in international organizations and societies:

  • 1995-2001, Member, Council of International Union of Immunological Societies
  • 1999-2003, Member, External Advisory Group (EAG), European Commission, Life Sciences “Control of Infectious Diseases”
  • International Society for Mucosal Immunology
  • International Society of Developmental and Comparative Immunology
  • Member, organizational committees of a number of international congresses and symposia
  • Member, Editorial Boards of, International Medical Magazine, Central-European Journal of Immunology, Alergie

Notable awards:

  • 1981, 1982, Awards of CSAS
  • 1987, J.E. Purkyně Medal, awarded by CSAS
  • 1996, Award, Gastroenterological Society
  • 1997, Award, Faculty of Medicine (for work in the area of mucosal immunity)
  • 1999, Medal, Nihon University, Tokyo, Japan

Selected publications:

  • Jelínková L., Tučková L., Cinová J., Flegelová Z., Tlaskalová-Hogenová H.: Gliadin stimulates human monocytes to production of IL-8 and TNF-á through a mechanism involving NF-ęB. FEBS Letters 571, 81-85, 2004
  • D. Sánchez, L. Tučková, Th. Mothes, W. Kreisel, Z. Beneš, H. Tlaskalová-Hogenová: Epitopes of calreticulin recognised by IgA autoantibodies from patients with hepatic and coeliac disease. J. Of Autoimmunity 21, 383-392, 2003
  • H. Tlaskalová-Hogenová, L. Tučková, R. Lodinová-Žádníková, R. Štěpánková, B. Cukrowska, D. P. Funda, I. Stříž, H. Kozáková, I. Trebichavský, D. Sokol., Z. Řeháková, J. Šinkora, P. Fundová, D. Horáková, L. Jelínková, D. Sánchez: Mucosal Immunity: Its role in defense and allergy. Int. Arch. Allergy Immunol. 128, 77-89 (2002)
  • D. P. Funda, L. Tučková, M. A. Farré, T. Iwase, I. Moro, H. Tlaskalová-Hogenová: CD14 is expressed and released as soluble CD14 by human intestinal epithelial cells in vitro: Lipopolysaccharide activation of epithelial cells revisited. Infection and Immunity 69, 3772-3781 (2001)
  • B. Singh, S. Read, Ch. Asseman, V. Malmstrom, Ch. Mottet, L. A. Stephans, R. Štěpánková, H. Tlaskalová, F. Powrie: Control of intestinal inflammation by regulatory T cells. Immunol. Rev. 182, 190-200 (2001)
  • D. P. Funda, A. Kaas, T. Bock, H. Tlaskalová-Hogenová, K. Buschard: Gluten-free diet prevents diabetes in NOD mice. Diabetes/Metabolism Research and Reviews 15, 323-327 (1999)
  • S. Krupičková, L. Tučková, Z. Flegelová, M. Michalak, J. R. F. Walters, A. Whelan, J. Harries, J. Vencovský, H. Tlaskalová-Hogenová: Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac diasease. Gut 44, 168-173 (1999)
  • H. Tlaskalová-Hogenová, R. Štěpánková, L. Tučková, B. Cukrowska, T. Hudcovic, F. Bendjelloul, P. Malý, M. Jirkovská, V. Mandys, O. Kofroňová, E. F. Verdú, P. Berčík, M. Farre, L. Prokešová, D. P. Funda, H. Kozáková, P. Michetti, J. Cebra: Effector mechanisms in intestinal immunity and inflammation. In: Innovative concepts in inflammatory bowel diseases (Emmrich et al., Eds.), Kluwer Academic Publishers, Dordrecht/Boston/London 1999, pp. 74-83
  • J. Mestecky, M. Russell, S. Jackson, S. Michalak, H. Tlaskalová-Hogenová, J. Šterzl (Eds.): Advances in Mucosal Immunology. Plenum Press, New York 1995
  • H. Tlaskalová-Hogenová, J. Šterzl, R. Štěpánková, V. Dlabač, V. Větvička, P. Rossmann, L. Mandel, J. Rejnek: Development of immunological capacity under germ-free and conventional conditions. Ann. N. Y. Acad. Sci. 409, 96-113 (1983)
  • M. Holub, P. Rossmann, H. Tlaskalová, H. Vidmarová: Thymus rudiment of the athymic nude mouse. Nature 256, 491-493 (1975)

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News

25.07.19

Luboš Perek is celebrating his 100th year

Founding fellow of the Learned Society and its doyen, astronomer doc. RNDr. Luboš Perek, DrSc, is celebrating his 100th birthday on 26 July 2019. He is an indelible part of history as the person who helped define cosmic space, he was the first to point out the issue of cosmic waste and was also a teacher to the most important Czechoslovak astronomers. Let us express our respect and admiration of the extraordinary scientific career of a person who worked tirelessly and continues to work. The Learned Society wishes Mr Perek health, optimism and joy in the oncoming years.

23.07.19

The Academy of Sciences of the Czech Republic has appealed to the Hungarian President to support academic freedom

On Friday 19 July the Academy of Sciences of the Czech Republic and the Learned Society of the Czech Republic sent a letter to Hungarian President János Ánder, in which they state their concerns regarding the situation in respect to management and funding of scientific activities in Hungary. An act, according to which not the Academy of Sciences, but a thirteen-member political committee, will decide on research, funding of scientific activities and establishment or closure of scientific workplaces, will come into force on 1 September.

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