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Vojtěšek Bořivoj

RNDr., DrSc.
Born October 25, 1960

  • Molecular oncology
  • Member of Learned Society since 2003

Educational and professional preparation:

  • 1976-1979, graduate, academic secondary school, Břeclav;
  • 1979-1984, Faculty of Natural Science, Department of Molecular Biology, Jan Evangelista Purkyně University, Brno;
  • 1985, RNDr.; 1990 CSc.;
  • 1996, DrSc., scientific field of oncology, Academy of Sciences of Czech Republic (AC CR), Prague and Slovak Academy of Sciences Bratislava.

Employment and academic positions:

  • 1985-present, Masaryk Memorial Cancer Institute (MMCI), Brno (formerly the Research Institute of Clinical and Experimental Oncology);
  • 1985-1999, principal scientist, MMCI;
  • 1999-2000, Head, Department of Cellular and Molecular Oncology, MMCI;
  • 2001-present, Head, working group, Biology of Tumours and Proteomics, MMCI

Membership in selected domestic scientific bodies:

  • 1993-present, member, Scientific Council, MMCI
  • 1999-2002, member, Scientific Council, Second Faculty of Medicine, Charles University (FM CU), Prague
  • 2003-present, member, Scientific Council, Faculty of Science, Palacký University, Olomouc
  • 2003-present, member, Scientific Council of Biophysical Institute, AS CR, Brno
  • 2003-present, member, Scientific Council, Institute of Animal Physiology, AS CR, Liběchov

Membership and positions in international organizations and societies:

  • Member, European Association for Cancer Research (EACR)

Notable awards:

  • 1996, Award, Minister of Health, Ministry of Health
  • 1999, Award, Minister of Health, Ministry of Health
  • 2001, Award, Minister of Health, Ministry of Health
  • 2003, Award, Minister of Health, Ministry of Health

Selected publications:

  • B. Vojtesek, J. Bartek, C. A. Midgley, D. P. Lane: An immunochemical analysis of human p53: New monoclonal antibodies and epitope mapping using recombinant p53. J. Immunol. Methods 151, 237-244 (1992)
  • B. Vojtesek, D. P. Lane: Regulation of p53 protein expression in human breast cancer cell lines. J. Cell Science 105, 607-612 (1993)
  • B. Vojtesek, C. J. Fisher, D. M. Barnes, D. P. Lane: Comparison between p53 staining in tissue sections and p53 proteins levels measured by an ELISA technique. Br. J. Cancer 67, 1254-1258 (1993)
  • K. H. Vousden, B. Vojtesek, CH. Fisher, D. P. Lane: HPV-16E7 or adenovirus E1A can overcome the growth arrest of cells immortalized with a temperature-sensitive p53. Oncogene 8, 1697-1702 (1993)
  • B. Vojtesek, H. Dolezalova, L. Lauerova, M. Svitakova, P. Havliš, J. Kovarik, C. A. Midgley, D. P. Lane: Conformational changes in p53 analysed using new antibodies to the core DNA binding domain of the protein. Oncogene 10, 389-393 (1995)
  • D. Niewolik, B. Vojtesek, J. Kovarik: p53 derived from human tumour cell lines and containing distinct point mutations can be activated to bind its consensus target sequence. Oncogene 10 , 881-890 (1995)
  • V. Kotala, S. Uldrijan, M. Horký, M. Trbůšek, M. Strnad, B. Vojtěšek: Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases. Cell. Mol. Life. Sci. 9, 1333-13339 (2001)
  • R. Nenutil, P. Ceskova, P. J. Coates, K. Nylander, B. Vojtesek: Differential Expression of p73alpha in Normal Ectocervical Epithelium, Cervical Intraepithelial Neoplasia, and Invasive Squamous Cell Carcinoma. Int. J. Gynecol Pathol. 22(4), 386-392 (2003)
  • M.A. Sheard, S. Uldrijan, B. Vojtesek.: Role of p53 in regulating constitutive and X-radiation-inducible CD95 expression and function in carcinoma cells. Cancer Res. 63(21), 7176-7184 (2003)
  • S. Pospisilova, V. Brazda, K. Kucharikova, M.G. Luciani, T.R. Hupp, P. Skladal, E. Palecek, B. Vojtesek: Activation of the DNA-binding ability of latent p53 protein by protein kinase C is abolished by protein kinase CK2. Biochem J. 378 (Pt 3), 939-947 (2004)

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News

25.07.19

Luboš Perek is celebrating his 100th year

Founding fellow of the Learned Society and its doyen, astronomer doc. RNDr. Luboš Perek, DrSc, is celebrating his 100th birthday on 26 July 2019. He is an indelible part of history as the person who helped define cosmic space, he was the first to point out the issue of cosmic waste and was also a teacher to the most important Czechoslovak astronomers. Let us express our respect and admiration of the extraordinary scientific career of a person who worked tirelessly and continues to work. The Learned Society wishes Mr Perek health, optimism and joy in the oncoming years.

23.07.19

The Academy of Sciences of the Czech Republic has appealed to the Hungarian President to support academic freedom

On Friday 19 July the Academy of Sciences of the Czech Republic and the Learned Society of the Czech Republic sent a letter to Hungarian President János Ánder, in which they state their concerns regarding the situation in respect to management and funding of scientific activities in Hungary. An act, according to which not the Academy of Sciences, but a thirteen-member political committee, will decide on research, funding of scientific activities and establishment or closure of scientific workplaces, will come into force on 1 September.

07.07.19

The loss of Learned Society Fellow prof. Josef Koutecký

We regret to inform that prof. Josef Koutecký, a fellow of the Learned Society, a renowned physician and the founder of paediatric oncology in this country, passed away on 5 July 2019 at the age of 88. He founded paediatric oncology here in 1964 and a separate paediatric oncology department was then established at the Faculty Hospital in Motol, Prague in 1978.