prof., RNDr., CSc.
Born February 18, 1955 in Prague
- Biochemistry, plant molecular physiology: Molecular mechanisms of action of plant signalling compounds (phytohormones)
- Member of Learned Society since 2017
Educational and professional preparation
- 1974-1979 Charles University, Faculty of Science, Prague, Czechoslovakia. Degree in chemistry (specialization: biochemistry) (RNDr., equivalent of M.Sc.).
- 1979-1982 Czechoslovak Academy of Sciences; postgraduate studies. Dissertation thesis: “Auxin binding sites in tobacco cell culture and wheat seedlings”
- 1983 Candidate of science degree (CSc. - equivalent to Ph.D.) in biology (specialization: plant physiology).
Employment and academic positions
- 1982-1983: Institute of Experimental Botany, Cs. Acad. Sci. (IEB) in Prague, assistant-researcher.
- (1983-1984: Maternity leave)
- 1985-1987: Scientist at the IEB: Auxin and auxin receptors in relation to development of plant cells (tobacco cell cultures) and plant organs (coleoptiles and primary leaves of wheat).
- (1987-1989: Maternity leave)
- Since 1989: Scientist at the IEB (since 1993 of the Czech Academy of Sciences, CAS), Prague: Co-action of auxins and cytokinins at control of plant cell development, auxin and cytokinin metabolisms and signalling, molecular mechanisms of auxin and cytokinin translocation across membranes in plant cells.
- Since 1997: Member of Laboratory of Hormonal Regulations in Plants of the IEB, head of the group focused on molecular mechanisms of auxin and cytokinin action and transport in plant cells.
- 2001-2012: Part-time contract (10-25%) at the Department of Plant Physiology (now Department of Experimental Plant Biology), Faculty of Science, Charles University in Prague – scientist, from 2005 associate professor.
- 2003-2007: Deputy Directress of the IEB.
- 2004: Named Associate Professor (docent, plant anatomy and physiology) at the Faculty of Science, Charles University, Prague.
- 2004-2016: Head of the Laboratory of Hormonal Regulations in Plants of the IEB.
- 2007-2012: Directress of the IEB.
- 2012-2017: Contract (part-time) at the Biology Centre of the CAS – senior scientist.
- 2013: Named Professor (Plant Physiology and Anatomy) at Charles University at Prague.
- 2013-2017: Member of the Academy Council of the CAS (and part-time at the IEB).
- Since March 25, 2017: President of the CAS.
Membership in selected domestic scientific bodies
- 1992-1993, 1996-2002: Member (1998-2002 - Chair) of the Scientific Board of the IEB.
- 1998-2013: Co-editor of international scientific journal Biologia Plantarum.
- 1998-2000: Member (2000 - Chair) of the Discipline Committee no. 6 (General Biology) of the Grant Agency of the CAS.
- Since 2005: Member of the Discipline Committee of the doctoral study programme „Plant Anatomy and Physiology“ at the Faculty of Science of Charles University in Prague.
- 2005-2011, 2013: Member of the Editorial Board of the international scientific journals Plant Growth Regulation (Managing Editor, until 2013) and South African Journal of Botany (until 2011) (both Springer).
- Since 2010: Member of Scientific Council of the Faculty of Science of Palacký University in Olomouc.
- Since 2010: Member of the Discipline Committee and Commission for State Exams of the specialisation P1507 V001 „Plant Anatomy and Physiology“ within the study programme P1507 „Botany“ at the Faculty of AgriSciences of Mendel University in Brno.
- 2011-2012: Member of the Coordination Council of Experts for the National Research Priorities of the Czech Republic (Priorities 2030).
- Since 2012: Member of the Discipline Committee of the doctoral study programme „Biochemistry“ at the Faculty of Science of Charles University in Prague.
- Since 2014: Member of Scientific Council of Palacký University in Olomouc.
- 2015-2017: Czech Science Foundation - member (2016 – deputy chair) of the panel no. 501.
- 2015-2017: Member of the Commission of Evaluation of Research Organizations and Completed Programmes, of the Research and Development Council - the advisory body to the Government of the Czech Republic.
- Since 2017: Member of Scientific Council of Masaryk University in Brno, and Scientific Council of the University of South Bohemia in České Budějovice.
- Continuously: Member of the Czech Society for Experimental Plant Biology, and the Czech Society for Biochemistry and Molecular Biology.
Membership and positions in selected international organizations and societies
- European Research Council (ERC): Starting Grants 2014, 2016 - LS3 panel member; Starting Grants 2013, 2015 - panel evaluator.
- European Commission: FP7 – Marie Curie Fellowships – panel member (life sciences, LIV - 2008-2013); Horizon 2020 – Marie Sklodowska-Curie Individual Fellowships - panel member (life science, LIV - 2014, 2016).
- 1986 Award of the Czech Literary Foundation, Section for scientific literature, for the paper: Zažímalová E, Kutáček M: Auxin-binding site in wheat shoots: Interactions between indol-3-ylacetic acid and its halogenated derivatives. - Biol. Plant. 27: 114-118, 1985.
- 1996 Professor Silvester Prát Award (supported byt the Swiss L'Association Jan Hus, president François Brélaz) for „the best Czech article in plant physiology published in 1994 or 1995“. Paper awarded: Zažímalová E, Opatrný Z, Březinová A, Eder J: The effect of auxin starvation on the growth of auxin-dependent tobacco cell culture: dynamics of auxin reception and endogenous free IAA content. - J. Exp. Bot. 46: 1205-1213, 1995.
- 2007 Paper by Petrášek et al., Science 312: 914-918, 2006 (Zažímalová – corresponding author) became the „New Hot Paper“ according to ESI in July 2007 (Essential Science Indicators) (http://www.esi-topics.com/nhp/2007/july-07-EvaZazimalova.html)
- Petrášek J, Černá A, Schwarzerová K, Elčkner M, Morris DA, Zažímalová E*: Do Phytotropins Inhibit Auxin Efflux by Impairing Vesicle Traffic? - PLANT PHYSIOLOGY 131: 254-263, 2003.
- Paciorek T, Zažímalová E, Ruthardt N, Petrášek J, Stierhof Y.-D, Kleine-Vehn J, Morris DA, Emans N, Jürgens G, Geldner N, and Friml J: Auxin inhibits endocytosis and promotes its own efflux from cells. – NATURE 435: 1251-1256, 2005.
- Petrášek J, Mravec J, Bouchard R, Blakeslee JJ, Abas M, Seifertová D, Wisniewska J, Tadele Z, Kubeš M, Čovanová M, Dhonukshe P, Skůpa P, Benková E, Perry L, Křeček P, Lee OR, Fink GR, Geisler M, Murphy AS, Luschnig C, Zažímalová E*, Friml J: PIN proteins perform a rate-limiting function in cellular auxin efflux. – SCIENCE 312: 914-918, 2006.
- Mravec J, Skůpa P, Bailly A, Hoyerová K, Křeček P, Bielach A, Petrášek J, Zhang J, Gaykova V, Stierhof Y-D, Dobrev PI, Schwarzerová K, Rolčík J, Seifertová D, Luschnig Ch, Benková E, Zažímalová E, Geisler M & Friml J: Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter. – NATURE 459 (7250): 1136-1140, 2009.
- Křeček P, Skůpa P, Libus J, Naramoto S, Tejos R, Friml J, Zažímalová E: Protein family review: The PIN-FORMED (PIN) protein family of auxin transporters. - GENOME BIOLOGY 10: 249.1, 2009.
- Zažímalová E*, Murphy AS, Yang H, Hoyerová K, Hošek P: Auxin Transporters—Why So Many? – COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY 2: 1-14, 2010.
- Hošek P, Kubeš M, Laňková M, Dobrev PI, Klíma P, Kohoutová M, Petrášek J, Hoyerová K, Jiřina M, Zažímalová E: Auxin transport on cellular level: New insights supported by mathematical-modelling. – JOURNAL OF EXPERIMENTAL BOTANY 63: 3815–3828, 2012.
- Barbez E, Kubeš M, Rolčík J, Beziat C, Pěnčík A, Wang B, Ruiz Rosquete M, Zhu J, Dobrev PI, Lee Y, Zažímalová E, Petrášek J, Geisler M, Friml J, Kleine-Vehn J: A novel putative auxin carrier family regulates intracellular auxin homeostasis in plants. – NATURE 485: 119-122, 2012.
- Leitner J, Petrášek J, Tomanov K, Retzer K, Pařezová M, Korbei B, Bachmair A, Zažímalová E, and Luschnig Ch: Lysine63-linked ubiquitylation of PIN2 auxin carrier protein governs hormonally controlled adaptation of Arabidopsis root growth. - PROC. NATL. ACAD. SCI. U. S. A. 109: 8322–8327, 2012.
- Simon S, Skůpa P, Viaene T, Zwievka M, Tejos R, Klíma P, Čarná M, Rolčík J, De Rycke R, Moreno I, Dobrev PI, Orellana A, Zažímalová E, Friml J: PIN6 auxin transporter at endoplasmic reticulum and plasma membrane mediates auxin homeostasis and organogenesis in Arabidopsis. – NEW PHYTOLOGIST 211 (1): 65-74, 2016.