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Novotný Miloš Vlastislav

Professor, RNDr, Dr.Sc., Dr.honoris causa (mult.)
Born on April 19, 1942, in Brno

  • Analytical chemistry, biochemistry
  • Foreign Member of the Learned Society since 2004

Educational and professional preparation:

  • Graduated in 1959, Gymnasium Brno-Husovice
  • Graduated in 1965 at the University of Brno (now Masaryk University); RNDr 1967.
  • 1965 – 1968, on research staff of the Institute of Analytical Chemistry, Czechoslovak Academy of Sciences, Brno
  • 1968 – 1969, Research Associate, Royal Karolinska Institute, Stockholm, Sweden
  • 1969 – 1971, Robert Welch Postdoctoral Fellow, University of Houston, Texas

Employment and academic positions:

Since 1971 on the faculty of Indiana University (Bloomington, Indiana), as Assistant Professor of Chemistry (1971 – 1974), Associate Professor (1974 – 1978), Professor of Chemistry (1978 – l988), James H. Rudy Professor (1988 – 1999), Distinguished Professor (1999 – present), Lilly Chemistry Alumni Chair (2000 – present), Adjunct Professor of Medicine, Indiana University School of Medicine, Indianapolis (2004 – present).

Membership in national and international societies:

  • American Chemical Society, since 1971
  • Mars Viking Lander Science Team, NASA, Associate Member, 1972 – 1974
  • Gordon Conference on Analytical Chemistry, Chairman in 1980
  • American Association for the Advancement of Science, elected as Fellow in 1989
  • Royal Society for Sciences (Sweden), elected as Foreign Member in 1999
  • Slovak Pharmaceutical Society, Honorary Member, 2004

Notable awards :

  • 1984: M.S. Tswett Award and Medal for Chromatography
  • 1986: American Chemical Society Award in Chromatography
  • 1988: ISCO Award in Biochemical Instrumentation
  • 1988: Chemical Instrumentation Award of the American Chemical Society
  • 1991: Marcel J.E. Golay Award and Medal for Capillary Chromatography
  • 1991: Doctor honoris causa, Uppsala University, Sweden
  • 1992: American Chemical Society Award in Separation Science and Technology
  • 1992: Doctor honoris causa, Masaryk University
  • 1994: R&D Magazine Scientist of the Year Award
  • 1994: M.S. Tswett Memorial Medal of the Russian Federation
  • 1994: A.J.P. Martin Gold Medal (United Kingdom)
  • 2000: COLACRO (Congreso Latinoamericano de Cromatografia ) Merit Medal
  • 2003: Tracy M. Sonneborn Award for Outstanding Research and Teaching, Indiana University
  • 2006: American Chemical Society Award in Analytical Chemistry
  • 2007: Doctor honoris causa, Charles University

Selected publications:

  • Z. Kyselova, Y. Mechref, M. Al Bataineh, L. E. Dobrolecki, R.J. Hickey, C.J. Sweeney, M.V. Novotny: Alterations in the human blood serum glycome as a consequence of prostate cancer. J. Proteome Res. (2007) ; ASAP Article; DOI: 10.1021/pr060664t
  • Milan Madera, Yehia Mechref, Iveta Klouckova, and Milos V. Novotny: Semiautomated high-sensitivity profiling of human blood serum glycoproteins through lectin preconcentration and multidimensional chromatography/tandem mass spectrometry, J. Proteome Research 5, 2348-2363 (2006)
  • M. Madera, Y. Mechref and M. V. Novotny: Combining lectin microcolumns with high-resolution separation techniques for enrichment of glycoproteins and glycopeptides. Anal. Chem. 77, 4081 (2005)
  • M.V. Novotny: Pheromones, binding proteins and receptor responses in rodents. Biochem. Soc. Transactions 31, 117 (2003)
  • Y. Mechref and M.V. Novotny: Structural investigations of glycoconjugates at high sensitivity. Chemical Reviews, 102(2) 321 (2002)
  • M. Sam, S. Vora, B. Malnic, W. Ma, M. V. Novotny, and L. B. Buck: Odorants may arouse instinctive behaviours. Nature 12, 142 (2001)
  • D.E. Timm, L.J. Baker, H. Mueller, L. Zidek, M.V. Novotny: Structural basis of pheromone binding to mouse major urinary protein (MUP-I). Protein Science 10, 997 (2001)
  • T. Leinders-Zufall, A. P. Lane, A. C. Puche, W. Ma, M. V. Novotny, M. T. Shipley and F. Zufall: Ultrasensitive and selective detection of putative pheromones by mammalian vomeronasal neurons. Nature 405, 792 (2000)
  • M. Novotny, W. Ma, B. Jemiolo, D. Wiesler, S. Harvey, F. Xu, T.-M. Xie and M. Carmack: A unique urinary constituent, 6-hydroxy-6-methyl-3-heptanone, is a pheromone that accelerates puberty in female mice. Chemistry & Biology 6, 377 (1999)
  • L. Zidek, M.J. Stone, S.M. Lato, A.D. Ellington, and M.V. Novotny: NMR mapping of recombinant mouse major urinary protein I binding site occupied by a pheromone, 2-sec.butyl-4,5-dihydrothiazole. Biochemistry 38, 9850 (1999)
  • M.V. Novotny, W. Ma, D. Wiesler, and L. Zidek: Positive identification of the puberty-accelerating pheromone of the house mouse: the volatiles associating with the major urinary protein. Proc. Roy. Soc. Lond. B 266, 2017 (1999)
  • L. Zidek, M. V. Novotny, and M. J. Stone: Increased protein backbone conformational entropy upon hydrophobic ligand binding. Nature Structural Biology 6, 1118 (1999)
  • M.V. Novotny: Capillary biomolecular separations. J. Chromatogr. B 689, 55 (1997)
  • P. Chen, D. Wiesler, J. Chmelik and M. Novotny: Substituted 2-hydroxy-1,2-dihydropyrrol-3-ones: fluorescent markers pertaining to oxidative stress and aging, Chem. Res. Toxicol. 9(6) 970 (1996)
  • M.V. Novotny, T.-M. Xie, S. Harvey, D. Wiesler, B. Jemiolo, & M. Carmack: Stereoselectivity in mammalian chemical communication: male mouse pheromones. Experientia 51, 738 (1995)
  • J. Sudor and M. V. Novotny: End-label, free-solution capillary electrophoresis of highly charged oligosaccharides. Anal. Chem., 67, 4205 (1995)
  • B. Jemiolo and M. Novotny: Inhibition of sexual maturation in juvenile male and female mice by a chemosignal of female origin. Physiol. Behav. 55, 519 (1994)
  • M. Stefansson and M. Novotny: Electrophoretic resolution of monosaccharide enantiomers in borate-oligosaccharide complexation media. J. Am. Chem. Soc. 115, 11573 (1993)
  • K. Cobb and M. Novotny: Peptide mapping of complex proteins at the low-picomole level, with capillary electrophoretic separations. Anal. Chem. 64, 879 (1992)
  • J.P. Liu, O. Shirota, D. Wiesler, and M. Novotny: Ultrasensitive fluorometric detection of carbohydrates as derivatives in mixtures separated by capillary electrophoresis. Proc. Nat. Acad. Sci. USA 88, 2302 (1991)
  • M. Novotny, S. Harvey, and B. Jemiolo: Chemistry of male dominance in the house mouse, Mus domesticus. Experientia 46, 109 (1990)
  • K.-E. Karlsson and M. Novotny: Separation efficiency of slurry-packed LC microcolumns with very small inner diameters. Anal. Chem. 60, 1662 (1988)
  • M. Novotny, B. Jemiolo, S. Harvey, D. Wiesler, and A. Marchlewska-Koj: Adrenal-mediated endogenous metabolites inhibit puberty in female mice. Science 231, 722 (1986)
  • B. Jemiolo, S. Harvey, and M. Novotny: Promotion of the Whitten effect in female mice by the synthetic analogs of male urinary constituents. Proc. Natl. Acad. Sci. USA 83, 4576 (1986)
  • M. Novotny, S. Harvey, B. Jemiolo, and J. Alberts: Synthetic pheromones that promote inter-male aggression in mice. Proc. Natl. Acad. Sci. USA 82, 2059 (1985)
  • G. Rhodes, M.L. Holland, D. Wiesler, M. Novotny, D.L. Felton, R.G. Peterson, and S.A. Moore: Structural relationships between the endogenous volatile urinary metabolites of experimentally diabetic rats and certain neurotoxins. Experientia 38, 75 (1982)
  • M. Novotny, S.R. Springston, P.A. Peaden, J.C. Fjeldsted, and M.L. Lee: Capillary supercritical-fluid chromatography. Anal. Chem. 53, 407A (1981)
  • T. Tsuda and M. Novotny: Packed microcapillary columns in high-performance liquid chromatography. Anal. Chem. 50, 271 (1978)
  • J.W. Jorgenson, M. Novotny, G.B. Copland, S.R. Wilson, S. Katona, and W.K. Whitten: Chemical scent constituents in the urine of the red fox (Vulpes vulpes L.) during the winter season. Science 199, 796 (1978)
  • M. Novotny ,J.M. Hayes, F. Bruner, and P.G. Simmonds: Gas-chromatographic column for the Viking 1975 molecular analysis experiment. Science 189, 215 (1975)

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News

25.07.19

Luboš Perek is celebrating his 100th year

Founding fellow of the Learned Society and its doyen, astronomer doc. RNDr. Luboš Perek, DrSc, is celebrating his 100th birthday on 26 July 2019. He is an indelible part of history as the person who helped define cosmic space, he was the first to point out the issue of cosmic waste and was also a teacher to the most important Czechoslovak astronomers. Let us express our respect and admiration of the extraordinary scientific career of a person who worked tirelessly and continues to work. The Learned Society wishes Mr Perek health, optimism and joy in the oncoming years.

23.07.19

The Academy of Sciences of the Czech Republic has appealed to the Hungarian President to support academic freedom

On Friday 19 July the Academy of Sciences of the Czech Republic and the Learned Society of the Czech Republic sent a letter to Hungarian President János Ánder, in which they state their concerns regarding the situation in respect to management and funding of scientific activities in Hungary. An act, according to which not the Academy of Sciences, but a thirteen-member political committee, will decide on research, funding of scientific activities and establishment or closure of scientific workplaces, will come into force on 1 September.

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