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Novotný Miloš Vlastislav

Professor, RNDr, Dr.Sc., Dr.honoris causa (mult.)
Born on April 19, 1942, in Brno

  • Analytical chemistry, biochemistry
  • Foreign Member of the Learned Society since 2004

Educational and professional preparation:

  • Graduated in 1959, Gymnasium Brno-Husovice
  • Graduated in 1965 at the University of Brno (now Masaryk University); RNDr 1967.
  • 1965 – 1968, on research staff of the Institute of Analytical Chemistry, Czechoslovak Academy of Sciences, Brno
  • 1968 – 1969, Research Associate, Royal Karolinska Institute, Stockholm, Sweden
  • 1969 – 1971, Robert Welch Postdoctoral Fellow, University of Houston, Texas

Employment and academic positions:

Since 1971 on the faculty of Indiana University (Bloomington, Indiana), as Assistant Professor of Chemistry (1971 – 1974), Associate Professor (1974 – 1978), Professor of Chemistry (1978 – l988), James H. Rudy Professor (1988 – 1999), Distinguished Professor (1999 – present), Lilly Chemistry Alumni Chair (2000 – present), Adjunct Professor of Medicine, Indiana University School of Medicine, Indianapolis (2004 – present).

Membership in national and international societies:

  • American Chemical Society, since 1971
  • Mars Viking Lander Science Team, NASA, Associate Member, 1972 – 1974
  • Gordon Conference on Analytical Chemistry, Chairman in 1980
  • American Association for the Advancement of Science, elected as Fellow in 1989
  • Royal Society for Sciences (Sweden), elected as Foreign Member in 1999
  • Slovak Pharmaceutical Society, Honorary Member, 2004

Notable awards :

  • 1984: M.S. Tswett Award and Medal for Chromatography
  • 1986: American Chemical Society Award in Chromatography
  • 1988: ISCO Award in Biochemical Instrumentation
  • 1988: Chemical Instrumentation Award of the American Chemical Society
  • 1991: Marcel J.E. Golay Award and Medal for Capillary Chromatography
  • 1991: Doctor honoris causa, Uppsala University, Sweden
  • 1992: American Chemical Society Award in Separation Science and Technology
  • 1992: Doctor honoris causa, Masaryk University
  • 1994: R&D Magazine Scientist of the Year Award
  • 1994: M.S. Tswett Memorial Medal of the Russian Federation
  • 1994: A.J.P. Martin Gold Medal (United Kingdom)
  • 2000: COLACRO (Congreso Latinoamericano de Cromatografia ) Merit Medal
  • 2003: Tracy M. Sonneborn Award for Outstanding Research and Teaching, Indiana University
  • 2006: American Chemical Society Award in Analytical Chemistry
  • 2007: Doctor honoris causa, Charles University

Selected publications:

  • Z. Kyselova, Y. Mechref, M. Al Bataineh, L. E. Dobrolecki, R.J. Hickey, C.J. Sweeney, M.V. Novotny: Alterations in the human blood serum glycome as a consequence of prostate cancer. J. Proteome Res. (2007) ; ASAP Article; DOI: 10.1021/pr060664t
  • Milan Madera, Yehia Mechref, Iveta Klouckova, and Milos V. Novotny: Semiautomated high-sensitivity profiling of human blood serum glycoproteins through lectin preconcentration and multidimensional chromatography/tandem mass spectrometry, J. Proteome Research 5, 2348-2363 (2006)
  • M. Madera, Y. Mechref and M. V. Novotny: Combining lectin microcolumns with high-resolution separation techniques for enrichment of glycoproteins and glycopeptides. Anal. Chem. 77, 4081 (2005)
  • M.V. Novotny: Pheromones, binding proteins and receptor responses in rodents. Biochem. Soc. Transactions 31, 117 (2003)
  • Y. Mechref and M.V. Novotny: Structural investigations of glycoconjugates at high sensitivity. Chemical Reviews, 102(2) 321 (2002)
  • M. Sam, S. Vora, B. Malnic, W. Ma, M. V. Novotny, and L. B. Buck: Odorants may arouse instinctive behaviours. Nature 12, 142 (2001)
  • D.E. Timm, L.J. Baker, H. Mueller, L. Zidek, M.V. Novotny: Structural basis of pheromone binding to mouse major urinary protein (MUP-I). Protein Science 10, 997 (2001)
  • T. Leinders-Zufall, A. P. Lane, A. C. Puche, W. Ma, M. V. Novotny, M. T. Shipley and F. Zufall: Ultrasensitive and selective detection of putative pheromones by mammalian vomeronasal neurons. Nature 405, 792 (2000)
  • M. Novotny, W. Ma, B. Jemiolo, D. Wiesler, S. Harvey, F. Xu, T.-M. Xie and M. Carmack: A unique urinary constituent, 6-hydroxy-6-methyl-3-heptanone, is a pheromone that accelerates puberty in female mice. Chemistry & Biology 6, 377 (1999)
  • L. Zidek, M.J. Stone, S.M. Lato, A.D. Ellington, and M.V. Novotny: NMR mapping of recombinant mouse major urinary protein I binding site occupied by a pheromone, 2-sec.butyl-4,5-dihydrothiazole. Biochemistry 38, 9850 (1999)
  • M.V. Novotny, W. Ma, D. Wiesler, and L. Zidek: Positive identification of the puberty-accelerating pheromone of the house mouse: the volatiles associating with the major urinary protein. Proc. Roy. Soc. Lond. B 266, 2017 (1999)
  • L. Zidek, M. V. Novotny, and M. J. Stone: Increased protein backbone conformational entropy upon hydrophobic ligand binding. Nature Structural Biology 6, 1118 (1999)
  • M.V. Novotny: Capillary biomolecular separations. J. Chromatogr. B 689, 55 (1997)
  • P. Chen, D. Wiesler, J. Chmelik and M. Novotny: Substituted 2-hydroxy-1,2-dihydropyrrol-3-ones: fluorescent markers pertaining to oxidative stress and aging, Chem. Res. Toxicol. 9(6) 970 (1996)
  • M.V. Novotny, T.-M. Xie, S. Harvey, D. Wiesler, B. Jemiolo, & M. Carmack: Stereoselectivity in mammalian chemical communication: male mouse pheromones. Experientia 51, 738 (1995)
  • J. Sudor and M. V. Novotny: End-label, free-solution capillary electrophoresis of highly charged oligosaccharides. Anal. Chem., 67, 4205 (1995)
  • B. Jemiolo and M. Novotny: Inhibition of sexual maturation in juvenile male and female mice by a chemosignal of female origin. Physiol. Behav. 55, 519 (1994)
  • M. Stefansson and M. Novotny: Electrophoretic resolution of monosaccharide enantiomers in borate-oligosaccharide complexation media. J. Am. Chem. Soc. 115, 11573 (1993)
  • K. Cobb and M. Novotny: Peptide mapping of complex proteins at the low-picomole level, with capillary electrophoretic separations. Anal. Chem. 64, 879 (1992)
  • J.P. Liu, O. Shirota, D. Wiesler, and M. Novotny: Ultrasensitive fluorometric detection of carbohydrates as derivatives in mixtures separated by capillary electrophoresis. Proc. Nat. Acad. Sci. USA 88, 2302 (1991)
  • M. Novotny, S. Harvey, and B. Jemiolo: Chemistry of male dominance in the house mouse, Mus domesticus. Experientia 46, 109 (1990)
  • K.-E. Karlsson and M. Novotny: Separation efficiency of slurry-packed LC microcolumns with very small inner diameters. Anal. Chem. 60, 1662 (1988)
  • M. Novotny, B. Jemiolo, S. Harvey, D. Wiesler, and A. Marchlewska-Koj: Adrenal-mediated endogenous metabolites inhibit puberty in female mice. Science 231, 722 (1986)
  • B. Jemiolo, S. Harvey, and M. Novotny: Promotion of the Whitten effect in female mice by the synthetic analogs of male urinary constituents. Proc. Natl. Acad. Sci. USA 83, 4576 (1986)
  • M. Novotny, S. Harvey, B. Jemiolo, and J. Alberts: Synthetic pheromones that promote inter-male aggression in mice. Proc. Natl. Acad. Sci. USA 82, 2059 (1985)
  • G. Rhodes, M.L. Holland, D. Wiesler, M. Novotny, D.L. Felton, R.G. Peterson, and S.A. Moore: Structural relationships between the endogenous volatile urinary metabolites of experimentally diabetic rats and certain neurotoxins. Experientia 38, 75 (1982)
  • M. Novotny, S.R. Springston, P.A. Peaden, J.C. Fjeldsted, and M.L. Lee: Capillary supercritical-fluid chromatography. Anal. Chem. 53, 407A (1981)
  • T. Tsuda and M. Novotny: Packed microcapillary columns in high-performance liquid chromatography. Anal. Chem. 50, 271 (1978)
  • J.W. Jorgenson, M. Novotny, G.B. Copland, S.R. Wilson, S. Katona, and W.K. Whitten: Chemical scent constituents in the urine of the red fox (Vulpes vulpes L.) during the winter season. Science 199, 796 (1978)
  • M. Novotny ,J.M. Hayes, F. Bruner, and P.G. Simmonds: Gas-chromatographic column for the Viking 1975 molecular analysis experiment. Science 189, 215 (1975)

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News

26.06.20

Reaction to the case of Tomáš Hudlický: Members of the Learned Society of the Czech Republic support the freedom of expression

„We believe that free exchange of ideas is a key condition for the pursuit of truth and that the honest opinions should be scrutinized, challenged or rebutted but not censored or suppressed,“ say 45 members of the Learned Society in a statement regarding the retracted opinion paper by Prof. Tomáš Hudlický.

24.06.20

The letter by Jan Konvalinka to the President and Vice-Chancellor of the Brock University regarding the retracted article of Prof. Tomáš Hudlický

Opinions could and should be challenged, questioned or refuted but never silenced. In order to be able to think, we have to have the right to inquire, question and even offend or be mistaken,” writes Assoc. Prof. Jan Konvalinka, a biochemist at the IOCB Prague and the Vice-Rector of the Charles University, to Gervan Fearon.

27.11.19

Prof Miroslav Bárta receives the Česká hlava National Government Award

Learned Society member, Prof. Mgr. Miroslav Bárta, Dr. (Charles University Faculty of Arts) received the Česká hlava (Czech Head) National Government Award on 25 November 2019. A renowned Czech Egyptologist and archaeologist, Professor Bárta researches the history of ancient civilisations, the human relationship to the natural environment, and also for many years the evolution of complex societies. He leads the Czech Institute of Egyptology for archaeological and environmental research in Egypt and Sudan. His principal research interest is the period of the pyramid builders of the Old Kingdom.