Říhová Blanka

Prof., RNDr., DrSc.
Born October 21, 1942 in Prague

• Immunology
• Member of Learned Society since 1996

Educational and professional preparation:

• 1959, graduate, Eighth eleven-year secondary school, Prague;
• 1964, graduate biology, Faculty of Science, Charles University (FS CU);
• 1966, RNDr., FS CU; 1969, CSc., Institute of Microbiology (IM), CSAS;
• 1993, Associate Professor in immunology, CU;
• 1993, DrSc., IM, CSAS; 2
• 2001, Full Professor in immunology, CU.

Employment and academic positions:

• 1963-1964, Research Assistant, FS CU;
• 1964-1966, IM, CSAS; Department of Immunology, study stay;
• 1966-1969, IM, CSAS; Department of Immunology, internal PhD student;
• 1969-1974, IM, CSAS; Department of Immunology, Postdoctoral Research Associate;
• 1974-1989, IM, CSAS; Principal Research Officer;
• 1987-1988, Oklahoma Medical Research Foundation; Senior Academic Visitor;
• 1989-1990, IM, CSAS; Department of Immunology, Leading Research Scientist;
• 1990-2000 Division of Immunology and Gnotobiology, Deputy Head;
• 1990-present, Head, Laboratory of Humoral Immunity, IM, AS CR;
• 1992-2000, Associate  Professor  of  pharmacy  and  pharmaceutical  chemistry, University of Utah, Salt Lake City (USA);
• 2003 visiting professor, University Paris-Nord, France (1 month);
• 2000-present, Director, IM, AS CR;
• 2000-present, Professor of pharmacy and pharmaceutical chemistry, University of Utah, Salt Lake City

Membership in domestic scientific bodies (selection):

• 1990-present, Member, Academy Assembly
• 1992-1992, Member, Scientific Council, IM, AS CR
• 1992-2000, Chairperson, Scientific Council, IM, AS CR
• 1994-2000, Member, Council for Sciences, AS CR
• 1996-2000, Member, Presidium, Grant Agency of Czech Republic
• 2000-2002, Member, Scientific Council, Institute of Chemical Technology (ICT)
• 2000-present, Member, Scientific Council FS CU
• 2001-present, Member, Scientific Council, Second Faculty of Medicine CU
• 2002-present, Member, Professional Commission for the Science of Living Nature, Council for Research and Development
• 2003-present, Member, Special Commission 08 - Infectious Diseases, Microbiology, Epidemiology and Immunology, Scientific Council, Internal Grant Agency of Ministry of Health of Czech Republic
• 2003-present, Member, Commission of the Council for Sciences, AS CR for Defence of Doctoral Theses in “Microbiology, Virology and Mycology”
• 2003-present, Member, Commission of the Scientific Council of AS CR for Defence of Doctoral Theses in „Immunology“
• 2003-present, Member, Scientific Council of AS CR for Defence of Doctoral Theses in „Biochemistry, Biophysics and Molecular Biology“
• 2003-present, Member, Special Subcommission 301, Grant Agency of Czech Republic (GA CR) in Molecular Biology, Genetics and Oncology

Membership and positions in international organizations and societies:

• 1963-present, Member, Czechoslovak Microbiological Society
• 1971-1979, Member, Biological Society, CSAS
• 1979-present, Czechoslovak (Czech) Immunological Society,
• 1989-1992, 1994-1997, 2000-present - member of the committee
• 1981-present, Member, J. E. Purkyně Medical Society
• 1982-present, Member, UPAC commission “Interaction of Polymers with Living Systems”
• 1982-present, Member, Chemical Society of CSAS (AS CR)
• 1985-present, Member of the International Society for Molecular Recognition
• 1993-present, Director, Society for Leukocyte Biology (Eastern European branch with registered address in Prague)
• 1993-present, Member, Society for Leukocyte Biology, International Relations Committee
• 1994-2000, Member, Sigma Xi
• 1995-present, Member, Controlled Release Society
• 1998-present, Member, European Science Foundation (ESF) Standing Committee for Life and Environmental Science (LESC)
• 1998-2002, member, All European Academies (ALLEA) Steering Committee
• 2000-present, Member, ESF/EURESCO Committee
• 2001-present, Member of the American Association for Cancer Research
• 2001-present, Member, American Diabetes Association
• 2002-present, Elected Member, European Academy of Sciences

Notable awards:

• 1972, Award, CSAS
• 1982, Award, CSAS
• 1983, Award, CSAS
• 1987, J. E. Purkyně Medal (for results obtained in biology) (CSAS)
• 2000, Medal, Faculty of Medicine, Chiang Mai University, Thailand
• 2002, Award, Czech Society of Allergology and Clinical Immunology (for contributions to the development of the field of allergology and clinical immunology)
• 2004, Prof. Dr. Wolf A. Kafka Verdienstmedaille

Selected publications:

• B. Říhová, J. Kopeček: Biological properties of targetable poly N-(2-hydroxypropyl)- methacrylamide - antibody conjugates. J. Control. Rel. 2, 289 (1985)
• B. Říhová, P. Kopečková, J. Strohalm, P. Rossmann, V. Větvička, J. Kopeček: Antibody directed affinity therapy applied to the immune system: In vivo effectiveness and limited toxicity of daunomycin conjugated to HPMA copolymers and targeting antibody. Clin. Immunol. Immunopathol. 46, 100 (1988)
• B. Říhová, K. Ulbrich, J. Strohalm, V. Větvička, M. Bilej, R. Duncan, J. Kopeček: Biocompatibility of N-(2-hydroxypropyl)methacrylamide copolymers containing adriamycin. Biomaterials 10, 335 (1989)
• B. Říhová, N.L. Krinick, J. Kopeček: Targetable photoactivatable drugs. J. of Material Science. Materials in Medicine 2, 238 (1991)
• B. Říhová, A. Jegorov, J. Strohalm, V. Maťha, P. Rossmann, L. Fornůsek, K. Ulbrich: Antibody-targeted cyclosporin A. J. Control. Rel. 19, 25 (1992)
• B. Říhová, J. Šrogl, M. Jelínková, M. Burešová, V. Šubr, K. Ulbrich: HPMA-based biodegradable hydrogels containing different forms of doxorubicin; antitumor effects and biocompatibility. Ann. NY. Acad. Sci.: Bioartificial Organs, Science, Medicine and Technology 831, 57 (1997)
• B. Říhová, J. Strohalm, K. Kubáčková, M. Jelínková, O. Hovorka, M. Kovář, D. Plocová, M. Šírová, M. Šťastný, L. Rozprimová, K. Ulbrich: Acquired and specific immunological mechanisms co-responsible for efficacy of polymerbound drugs. J. Control. Rel. 78, 97 (2002)
• B. Říhová, J. Strohalm, K. Kubáčková, M. Jelínková, L. Rozprimová, M. Šírová, D. Plocová, T. Mrkvan, M. Kovář,  J. Pokorná, T. Etrych, K. Ulbrich: Drug-HPMA-HuIg conjugates effective against human solid cancer. Polymer Drugs in the Clinical Stage (Maeda et al., Eds.). Kluwer Academic/Plenum Publishers, New York (2003), 125
• B. Říhová, J. Strohalm, J. Prausová, K. Kubáčková, M. Jelínková, L. Rozprimová, M. Šírová, D. Plocová, T. Etrych, V. Šubr, T. Mrkvan, M. Kovář, K. Ulbrich:  Cytostatic and  immunomobilizing  activities  of  polymer-bound  drugs: experimental and first clinical data. J. Control. Rel. 91, 1 (2003)
• B.  Říhová,  K.  Kubáčková:  Clinical  implications  of  N-(2-hydroxy-propyl)methacrylamide copolymers. Current Pharmaceutical Biotechnology 4, 311 (2003)