Kopeček Jindřich

Distinguished Professor, D.Sc.
Born January 27, 1940 in Strakonice

  • Chemist
  • Member of Learned Society since 1998
Institution:
  • Department of Pharmaceutics and Pharmaceutical Chemistry, Department of Bioengineering, University of Utah, Salt Lake City, Utah 84112, USA

Educational and professional preparation:

  • 1990, D.Sc., chemistry, Czechoslovak Academy of Sciences (CSAS);
  • 1967-1968, Post-doctoral Fellow, National Research Council of Canada, Ottawa;
  • 1965, Ph.D., macromolecular chemistry, Institute of Macromolecular Chemistry (IMC) CSAS;
  • 1961, M.S., macromolecular chemistry, Institute of Chemical Technology, Prague

Employment and academic positions:

  • 2002-present, Distinguished Professor of Pharmaceutics and Pharmaceutical Chemistry, Distinguished Professor of Bioengineering, University of Utah;
  • 1999-2004, Chairman, Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah;
  • 1989-2002, Professor of Pharmaceutics and Pharmaceutical Chemistry, Professor of Bioengineering, University of Utah;
  • 1986-present, Co-Director, Center for Controlled Chemical Delivery, University of Utah;
  • 1983-2000, Visiting Professor, Université Paris-Nord;
  • 1986-1988, University of Utah; 1999, Tokyo Women’s Medical University;
  • 1972-1988, Head, Laboratory, Institute of Macromolecular Chemistry, CSAS;
  • 1965-1972, Scientific Officer, Institute of Macromolecular Chemistry, CSAS

Membership and positions in international organizations and societies:

  • Controlled Release Society: President 1995-1996; Vice-President 1993-1994; member, Board of Governors 1988-1991; Chairman, Nagai Award Committee, 2002-present.
  • Member, Biomaterials Society
  • Member, American Association for the Advancement of Science
  • Member, American Association for Cancer Research
  • Member, American Association of Pharmaceutical Scientists
  • Member, Society for Molecular Recognition
  • Member, American Society for Photobiology

Notable awards:

  • 2004, Chair, Gordon Research Conference on Drug Carriers in Medicine and Biology
  • 2003-present,, Chair, National Institutes of Health, Biomaterials and Biointerfaces Study Section
  • 2003, Heyrovský Medal for merit in the chemical sciences, Academy of Sciences of the Czech Republic
  • 2003, AAPS PharmSci and AAPS PharmSciTech Outstanding Use of Technology, Award for best publication in AAPS PharmSci, American Association of Pharmaceutical Scientists
  • 2001, Paul Dawson Biotechnology Award, American Association of Colleges of Pharmacy
  • 2000, Millennial Pharmaceutical Scientist, Millennial World Congress of Pharmaceutical Sciences
  • 1999, Fellow of Biomaterials Science and Engineering, International Union of Societies of Biomaterials Science and Engineering
  • 1999, J. Heller Award for best publication in Journal of Controlled Release
  • 1999, Founders Award, Controlled Release Society
  • 1995, Clemson Award (for Basic Research, Society for Biomaterials)
  • 1995, Fellow, American Institute for Medical and Biological Engineering
  • 1994, Fellow, American Association of Pharmaceutical Scientists
  • 1993, Distinguished Research Award, University of Utah
  • 1992, Program Chairman, 19th International Symposium on Controlled Release of Bioactive Materials, Orlando, Florida
  • 1990, Barre’s Lecture, Université de Montreal

Member, Editorial Boards:

  • 1973-1996, Polymers in Medicine (Wroclaw)
  • 1986-1998, New Polymeric Materials
  • 1992-1998, Polymer Gels and Networks
  • 1980-present, Biomaterials
  • 1981-present, Critical Reviews in Therapeutic Drug Carrier Systems
  • 1984-present, Journal of Controlled Release
  • 1986-present, Journal of Bioactive and Compatible Polymers
  • 1987-present, Journal of Biomaterials Science
  • 1991-present, Drug Delivery
  • 1992-present, European Journal of Pharmaceutics and Biopharmaceutics
  • 1993-present, Bioconjugate Chemistry
  • 1995-present, Pharmaceutical Research
  • 1999-present, The AAPS Journal (formerly AAPS PharmSci)
  • 2001-present, Advanced Drug Delivery Reviews
  • 2002-present, Journal of Drug Delivery Science and Technology (formerly STP Pharma Sciences)
  • 2002-present, European Journal of Pharmaceutical Sciences

Research interests:

  • Biorecognition of Macromolecules
  • Bioconjugate Chemistry
  • Drug Delivery Systems
  • Genetically Engineered Materials
  • Self-Assembly of Macromolecules

Notable publications:

  • N. Nishiyama, A. Nori, A. Malugin, Y. Kasuya, P. Kopeckova, J. Kopecek: Free and N-(2-Hydroxypropyl)methacrylamide (HPMA) Copolymer-bound Geldanamycin Derivative Induce Different Stress Responses in A2780 Human Ovarian Carcinoma Cells. Cancer Res. 63, 7876-7882 (2003)
  • A. Nori, K.D. Jensen, M. Tijerina, P. Kopeckova, J. Kopecek, Tat Conjugated Synthetic Macromolecules Facilitate Cytoplasmic Drug Delivery to Human Ovarian Carcinoma Cells. Bioconjugate Chem. 14, 44-50 (2003)
  • J. Kopecek, Smart and Genetically Engineered Biomaterials and Drug Delivery Systems, Eur. J. Pharm. Sci. 20, 1-16 (2003)
  • D. Wang, M. Pechar, W. Li, P. Kopeckova, D. Brömme, J. Kopecek: Inhibition of Cathepsin K with Lysosomotropic Macromolecular Inhibitors, Biochemistry 41, 8849-8859 (2002)
  • A. Tang, J. Kopecek, Presentations of Epitopes on Peptide Scaffolds and Selection of Lymphoma-Targeting Moieties Based on Epitope Recognition. Biomacromolecules 3, 421-431 (2002)
  • J.-G. Shiah, M. Dvorak, P. Kopeckova, Y. Sun, C. M. Peterson, J. Kopecek: Biodistribution and Antitumor Efficacy of Long-Circulating N-(2-Hyd-roxy-propyl)methacrylamide Copolymer-Doxorubicin Conjugates in Nude Mice,
    Eur. J. Cancer
    37, 131-139 (2001)
  • T. Minko, P. Kopeckova, J. Kopecek: Efficacy of Chemotherapeutic Action of HPMA Copolymer-Bound Doxorubicin in a Solid Tumor Model of Ovarian Carcinoma.
    Int. J. Cancer, 86, 108-117 (2000)
  • J.-G. Shiah, Y. Sun, C. M. Peterson, R. C. Straight, J. Kopecek: Antitumor Activity of HPMA Copolymer-Meso Chlorin e6 and Adriamycin Conjugates in Combination Treatments. Clin. Cancer Res. 6, 1008-1015 (2000)
  • Z.-R. Lu, P. Kopeckova, J. Kopecek: Polymerizable Fab’ Antibody Fragments for Targeting of Anticancer Drugs. Nature Biotechnology 17, 1101-1104 (1999)
  • C. Wang, R. J. Stewart, J. Kopecek: Hybrid Hydrogels Assembled from Synthetic Polymers and Coiled-Coil Protein Domains. Nature 397, 417-420 (1999)

visit the website »

Zpět na seznam článků

Novinky

29.09.21

Krásné společenské stroje: pozvánka na diskusi o umělé inteligenci a algoritmické teorii her

Učená společnost Vás srdečně zve na diskusi "Krásné společenské stroje: umělá inteligence a algoritmická teorie her". Diskutovat bude pět světových expertů: Jiří Matas (ČVUT), Tomáš Mikolov (CIIRC), Martin Schmid (Google DeepMind), Jan Vondrák (Stanford Univ.) a Lenka Zdeborová (École Polytechnique Fédérale de Lausanne). Diskuse se uskuteční 19. 10. 2021 od 16.00 hod. v budově Akademie věd ČR, Národní 3, Praha 1 (místnost 206). Diskusi bude možno sledovat také na YouTube: http://spolecenske-stroje.jdem.cz.

Pozvánka (PDF)

29.09.21

Stříbrná medaile Senátu pro Helenu Illnerovou a Jiřího Grygara

Členové Učené společnosti prof. Helena Illnerová a dr. Jiří Grygar převzali 28. září 2021 z rukou předsedy Senátu PČR Miloše Vystrčila Stříbrnou pamětní medaili. Stříbrná medaile předsedy Senátu se uděluje od roku 2007 osobnostem z řad vědců, umělců, sportovců a dalším osobám, které vynikly ve svých oborech či vykonaly zvláštní čin. Od roku 2012 medaili uděluje předseda Senátu při příležitosti Dne české státnosti, tj. 28. září. Příležitostně může být předána během roku v případě návštěvy významných zahraničních osobností.

16.09.21

Pozvánka ke sledování online přednášky doc. RNDr. Filipa Matějky, Ph.D.: Ekonomie a lidská nepozornost

Učená společnost Vás srdečně zve ke sledování online přednášky doc. RNDr. Filipa Matějky, Ph.D. (CERGE-EI, Praha; Center for Economic and Policy Research, London): Ekonomie a lidská nepozornost. Přednášku je možné sledovat 21. 9. 2021 od 16:00 hod. na YouTube: http://matejka.jdem.cz

Pozvánka (PDF)